Evidence map›Paper›PMID 42343835›Full record

ArticleNan fang yi ke da xue xue bao = Journal of Southern Medical University2026

[Elevation of red blood cell distribution width to hematocrit ratio is associated with increased 28-day all-cause mortality in septic patients].

Ziyu Wang, Jingwen Wu, Hanbing Wang, Yan Xu, Chunling Jiang, Li Zhou

Abstract readEnglish Abstract
PubMed Full text at PMC Publisher
In one paragraph

Article in Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Ziyu WangDepartment of Anesthesiology, West China Medical Center, Chengdu 610041, China.
Jingwen WuDepartment of Anesthesiology, West China Medical Center, Chengdu 610041, China.
Hanbing WangWest China School of Medicine, Sichuan University, Chengdu 610041, China.
Yan XuDepartment of Anesthesiology, West China Medical Center, Chengdu 610041, China.
Chunling JiangDepartment of Anesthesiology, West China Medical Center, Chengdu 610041, China.
Li ZhouDepartment of Anesthesiology, West China Medical Center, Chengdu 610041, China.

Funding

National Natural Science Foundation of China 82002084 and 81971806
6 · The paper itself

Abstract

objectivesTo investigate the association between the red blood cell distribution width to hematocrit (RDW/HCT) ratio and 28-day all-cause mortality in patients with sepsis.

methodsA retrospective cohort study was conducted using the MIMIC-IV database (27 335 adult patients), and the eICU-CRD database was used for external validation (17 406 adult patients). The patients were grouped by RDW/HCT ratio quartiles. The primary outcome was 28-day all-cause mortality. Kaplan-Meier survival curves were used to assess the survival rates. Multivariable Cox regression and restricted cubic spline (RCS) analyses were performed to examine the association between RDW/HCT ratio and patient mortality. Subgroup analyses were conducted to assess the robustness of the findings.

resultsThe 28-day mortality rates were 19.3% in the MIMIC-IV cohort and 16.0% in the eICU-CRD cohort. In the MIMIC-IV cohort, Kaplan-Meier analysis showed that a higher RDW/HCT ratio was associated with an increased risk of 28-day mortality in septic patients (log-rank

Indexed as

Erythrocyte IndicesSepsisAdultAgedFemaleHematocritHumansMaleMiddle AgedPrognosisProportional Hazards ModelsRetrospective Studies28-day all-cause mortalityMIMIC-IV/ eICU-CRD databaseRed blood cell distribution width/hematocritSepsis

Identifiers

PMID42343835
PMCPMC13294752

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.