Evidence map›Paper›PMID 42344220›Full record

ArticleAdvances in oncology2025

Treatment of Isocitrate Dehydrogenase-Mutant Gliomas.

Sofia Chernet, Hannah Kim, Ankush Bhatia, Craig Horbinski, Karan Dixit

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advances in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sofia ChernetNorthwestern University Feinberg School of Medicine, Department of Neurology, 303 E. Chicago Ave., Chicago, IL 60611.
Hannah KimNorthwestern University Feinberg School of Medicine, Department of Neurology, 303 E. Chicago Ave., Chicago, IL 60611.
Ankush BhatiaUniversity of Wisconsin School of Medicine and Public Health, Department of Neurology, 600 Highland Ave., Madison, WI 53792.
Craig HorbinskiNorthwestern University Feinberg School of Medicine, Departments of Pathology and Neurosurgery, 303 East Superior St, Chicago, IL 60611.
Karan DixitNorthwestern University Feinberg School of Medicine, Department of Neurology, 710 North Lake Shore Dr, Room 1123, Chicago, IL 60611.

Funding

STINGing GBM: A First-in- Man Clinical Trial in Surgical Resectable Recurrent GBMP50CA221747 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Hui Zhang · 2018 to 2026
$21.4M
Targeting IDH mutations to improve seizure control in glioma patientsR01NS118039 · NINDS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI HORBINSKI, CRAIG MICHAEL, SWANSON, GEOFFREY T · 2020 to 2024
$2.2M
The Significance of Isocitrate Dehydrogenase Mutations in GliomasK08CA155764 · NCI · UNIVERSITY OF KENTUCKY · PI HORBINSKI, CRAIG MICHAEL · 2011 to 2015
$857k
NCI NIH HHS K08 CA155764NCI NIH HHS P50 CA221747NINDS NIH HHS R01 NS118039
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

2-HydroxyglutarateAstrocytomaGliomaIDH inhibitorsIDH mutationsOligodendrogliomaVorasidenib

Identifiers

PMID42344220
PMCPMC13290257

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.