Evidence map›Paper›PMID 42344366›Full record

ArticleFrontiers in cardiovascular medicine2026

Cardiac autonomic ganglion ablation for refractory coronary artery spasm after PCI: a case report.

Fuchao Qu, Shanshan Zhang, Xiufeng Li, Lili Chen, Jiageng Wang, Xiaohua Ma, Chenhui Liu, Yifei Liu, Yuanxin Wang, Leisheng Zhang and 1 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Fuchao Qu *Department of Cardiovascular Medicine, The Fourth People's Hospital of Jinan Affiliated to Shandong Second Medical University, Jinan, China.
Shanshan Zhang *Shandong Provincial Key Medical and Health Laboratory of Blood Ecology and Biointelligence, Jinan Key Laboratory of Medical Cell Bioengineering, Science and Technology Innovation Center, The Fourth People's Hospital of Jinan Affiliated to Shandong Second Medical University, Jinan, China.
Xiufeng Li *Department of Cardiovascular Medicine, The Fourth People's Hospital of Jinan Affiliated to Shandong Second Medical University, Jinan, China.
Lili ChenDepartment of Imaging, The First People's Hospital of Jinan, Jinan, Shandong, China.
Jiageng WangShandong Provincial Key Medical and Health Laboratory of Blood Ecology and Biointelligence, Jinan Key Laboratory of Medical Cell Bioengineering, Science and Technology Innovation Center, The Fourth People's Hospital of Jinan Affiliated to Shandong Second Medical University, Jinan, China.
Xiaohua MaDepartment of Cardiovascular Medicine, The Fourth People's Hospital of Jinan Affiliated to Shandong Second Medical University, Jinan, China.
Chenhui LiuDepartment of Cardiovascular Medicine, The Fourth People's Hospital of Jinan Affiliated to Shandong Second Medical University, Jinan, China.
Yifei LiuDepartment of Cardiovascular Medicine, The Fourth People's Hospital of Jinan Affiliated to Shandong Second Medical University, Jinan, China.
Yuanxin WangShandong Provincial Key Medical and Health Laboratory of Blood Ecology and Biointelligence, Jinan Key Laboratory of Medical Cell Bioengineering, Science and Technology Innovation Center, The Fourth People's Hospital of Jinan Affiliated to Shandong Second Medical University, Jinan, China.
Leisheng ZhangShandong Provincial Key Medical and Health Laboratory of Blood Ecology and Biointelligence, Jinan Key Laboratory of Medical Cell Bioengineering, Science and Technology Innovation Center, The Fourth People's Hospital of Jinan Affiliated to Shandong Second Medical University, Jinan, China.
Wenwei YueDepartment of Cardiovascular Medicine, The Fourth People's Hospital of Jinan Affiliated to Shandong Second Medical University, Jinan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 45-year-old male patient presented with recurrent nocturnal or early morning chest pain following coronary stent implantation, and the electrocardiogram findings were consistent with Wellens' syndrome. Due to a low baseline heart rate, the patient could not tolerate diltiazem, and the response to standard anti-spastic medical therapy was poor. Intracoronary ergonovine provocation testing induced severe spasms of the left anterior descending and left circumflex arteries and reproduced the patient's chest pain. Given the typical presentation of heightened vagal tone, catheter ablation of cardiac autonomic ganglia was performed under the guidance of a three-dimensional electroanatomical mapping system. Post-ablation, repeat ergonovine testing showed markedly attenuated coronary artery spasm that resolved spontaneously, and the patient experienced no chest pain. At the 2-month follow-up, angina had completely resolved. This case suggests that cardiac autonomic ganglion ablation may be a valuable non-pharmacological treatment option for patients with refractory vasospastic angina after PCI who exhibit heightened vagal tone.

Indexed as

catheter ablation of cardiac autonomic gangliacoronary artery spasmergonovine provocation testheightened vagal toneWellens syndrome

Identifiers

PMID42344366
PMCPMC13286847

What Socratic holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.