Evidence map›Paper›PMID 42344566›Full record

ReviewIndian journal of plastic surgery : official publication of the Association of Plastic Surgeons of India2026

Systematic Review of Stem Cells in Plastic, Reconstructive, and Aesthetic Surgery: Clinical Application in Anti-Aging Medicine.

Huntal Napoleon, Putra B Djohan, Evelyn Evelyn, Laveda Lypinsky, Stefani Luziani, Magistra C Margaretha

Abstract readReview
In one paragraph

Review in Indian journal of plastic surgery : official publication of the Association of Plastic Surgeons of India, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Huntal NapoleonDepartment of Plastic, Reconstruction, and Esthetic Surgery, Indonesia Police Central Bhayangkara Hospital, Jakarta, Indonesia.
Putra B DjohanDepartment of Medicine, Indonesia Police Central Bhayangkara Hospital, Jakarta, Indonesia.ORCID 0000-0001-6883-9572
Evelyn EvelynDepartment of Pharmacy, Indonesia International Institute for Life Sciences, Jakarta, Indonesia.
Laveda LypinskyDepartment of Medicine, Pelita Harapan Faculty of Medicine, Banten, Indonesia.
Stefani LuzianiDepartment of Medicine, Faculty of Medicine, Udayana University, Bali, Indonesia.
Magistra C MargarethaDepartment of Medicine, Indonesia Police Central Bhayangkara Hospital, Jakarta, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The application of stem cells in plastic, reconstructive, and aesthetic surgery has emerged as a promising frontier in anti-aging medicine. Stem cells, particularly adipose-derived stem cells (ADSCs) and mesenchymal stem cells (MSCs), are increasingly utilized for their regenerative properties, offering innovative solutions for a range of aesthetic and reconstructive challenges. Objective: This review explores the current and potential clinical applications of stem cells in plastic surgery, focusing on their role in grafting, facial rejuvenation, wound healing, soft tissue reconstruction, and hair restoration. Materials and Methods: A comprehensive literature analysis was conducted using the PRISMA algorithm, examining studies and clinical trials that evaluate the efficacy, safety, and outcomes of stem cell-based therapies in plastic surgery. Emphasis was placed on the therapeutic mechanisms of stem cells, including their ability to enhance tissue regeneration, reduce scarring, and improve graft survival. Results: Out of the 5,117 studies identified, 22 met the inclusion criteria, highlighting the diverse applications of stem cells in plastic surgery. These studies reported significant advancements in aesthetic and reconstructive outcomes. Conclusion: Stem cell therapies represent a transformative approach in plastic surgery, offering significant benefits in aesthetic enhancement and functional restoration. While current applications show promising results, ongoing research is essential to address regulatory issues, ethical considerations, and the need for standardized treatment protocols.

Indexed as

anti-agingcartilage regenerationfacial rejuvenationhair restorationplastic surgerysoft tissue reconstructionstem cellswound healing

Identifiers

PMID42344566
PMCPMC13290374

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.