Evidence map›Paper›PMID 42344635›Full record

ArticleAsian journal of transfusion science

Prevalence of hepatitis B and C markers in blood donors deferred from donating blood due to hepatitis-related risk factors.

Ushasree Ravula, Suchet Sachdev, Ajay Kumar Duseja, Arnab Pal, Jasmeet Kaur, Rekha Hans, Ratti Ram Sharma, Neelam Marwaha

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Article in Asian journal of transfusion science. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Ushasree RavulaDepartment of Transfusion Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Suchet SachdevDepartment of Transfusion Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Ajay Kumar DusejaDepartment of Hepatology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Arnab PalDepartment of Biochemistry, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Jasmeet KaurDepartment of Transfusion Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Rekha HansDepartment of Transfusion Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Ratti Ram SharmaDepartment of Transfusion Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Neelam MarwahaDepartment of Transfusion Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe donor selection criteria are developed to identify and defer the blood donors at risk of infections for an appropriate duration of time to allow time for the infectious agent to elicit an immune response for the purpose of diagnostic detection. MATERIALS AND

methodsThis was an observational study to compare the prevalence of markers of hepatitis B and hepatitis C in 1000 donors deferred on hepatitis-related risk factors, with 62,328 donors selected for donations on quality-assured enzyme-linked immunosorbent assay and individual unit nucleic acid testing (NAT).

resultsIn 1000 deferred donors, 8 (0.8%), 10 (1%), and 17 (1.7%) were reactive for hepatitis B surface antigen (HBsAg), anti-hepatitis C virus (HCV) antibodies, and initial NAT; 8 (0.8%) and 7 (0.7%) discriminated against hepatitis B virus (HBV) and HCV, respectively. In 62,328 selected donors, 260 (0.4%), 267 (0.4%), and 76 (0.12%) were reactive for HBsAg, anti-HCV antibodies, and initial NAT; 26 (0.04%) and 8 (0.01%) discriminated against HBV and HCV, respectively. NAT yield was 4 (0.4%,

conclusionThe study highlights the need for surveillance of hepatitis-related risk factors in the potential blood donor population to generate evidence for periodic updates to the donor selection criteria.

Indexed as

High-risk practicesnucleic acid testingserologytransfusion transmissible hepatitisTransfusion transmissible infections

Identifiers

PMID42344635
PMCPMC13290168

What Socratic holds

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LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.