SynthesisFrontiers in nutrition2026
Systematic review and meta-analysis of randomized controlled trials assessing the impact of fish consumption on micronutrient status of children.
Synthesis in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
4 authors.
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Abstract
Introduction: Fish consumption contributes to overall nutrient intake and health, but its effects on micronutrient status remain uncertain. We conducted a systematic review and meta-analysis to assess the impact of fish consumption on the micronutrient status of children. Methods: Three databases were searched (April 2025) for studies comparing biomarker-based micronutrient status among children (2-14 years) with fish versus low or no fish intake. Risk of bias was assessed using RoB2, and findings were synthesized through meta- and narrative analyses with GRADE evaluation. Results: Seven studies (six randomized controlled trials) met inclusion criteria, covering nine biomarkers, including 25(OH)D, urinary iodine concentration, ferritin, hemoglobin, retinol, beta-carotene, calcium, cobalamin, and folate. Three studies had low risk of bias, two moderate, and one high. Meta-analysis was possible only for vitamin D (25(OH)D, 1,074 participants), showing a pooled mean difference of 4.08 nmol/L (95% CI: 1.73-6.43) favoring fish consumption; sensitivity analysis (850 participants) yielded 3.46 nmol/L (95% CI: 1.03-5.65), with no heterogeneity. Results for other biomarkers were largely nonsignificant. Conclusion: Fish consumption modestly improves vitamin D status in children, though effects may lack clinical relevance. Evidence for other micronutrients is inconsistent, highlighting the need for more rigorous studies.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.