Evidence map›Paper›PMID 42344900›Full record

ArticleFrontiers in immunology2026

Chelerythrine enhances anti-fungi immunity in

Shenyuan Fan, Guohui Bai, Tingting Zhong, Yi Xiao, Yuan Tian

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shenyuan Fan *Key Laboratory of Oral Disease Research of the Education Department of Guizhou Province, School of Stomatology, Zunyi Medical University, Zunyi, Guizhou, China.
Guohui BaiKey Laboratory of Oral Disease Research of the Education Department of Guizhou Province, School of Stomatology, Zunyi Medical University, Zunyi, Guizhou, China.
Tingting ZhongKey Laboratory of Oral Disease Research of the Education Department of Guizhou Province, School of Stomatology, Zunyi Medical University, Zunyi, Guizhou, China.
Yi XiaoThe Key Laboratory of Pharmaceutical Research for Tumor Prevention and Treatment of the Education Department of Guizhou Province, Zunyi Medical University, Zunyi, Guizhou, China.
Yuan TianKey Laboratory of Oral Disease Research of the Education Department of Guizhou Province, School of Stomatology, Zunyi Medical University, Zunyi, Guizhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chelerythrine is a natural benzophenanthridine alkaloid with various pharmacological activities. However, whether Chelerythrine can influence innate immunity and its underlying molecular mechanisms remain unclear. In this study, we found that 10 μM Chelerythrine significantly extended the lifespan of

Indexed as

BenzophenanthridinesCaenorhabditis elegansCaenorhabditis elegans ProteinsCandida albicansCandidiasisFatty AcidsForkhead Transcription FactorsReceptors, Cytoplasmic and NuclearAnimalsImmunity, InnateSignal TransductionBenzophenanthridinesCaenorhabditis elegans Proteinschelerythrinedaf-16 protein, C elegansFatty AcidsForkhead Transcription FactorsNHR-49 protein, C elegansReceptors, Cytoplasmic and NuclearCaenorhabditis elegansChelerythrineDAF-16/FOXOinnate immunityNHR-49

Identifiers

PMID42344900
PMCPMC13286803

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.