Evidence map›Paper›PMID 42345040›Full record

ArticlePNAS nexus2026

Comparative analysis of gene expression in mammalian claustrum subdivisions.

Chao Fang, Miao Li, Lanxiang Li, Feng Liang, Jinfeng Huang, Li Lu, Zhonghua Lu, Hong Wang, Robert K Naumann

Abstract read
In one paragraph

Article in PNAS nexus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Chao FangThe Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.ORCID https://orcid.org/0000-0002-9175-1007
Miao LiThe Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.
Lanxiang LiThe Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.
Feng LiangThe Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.
Jinfeng HuangThe Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.
Li LuKunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan 650201, China.ORCID https://orcid.org/0000-0003-2495-483X
Zhonghua LuThe Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.
Hong WangThe Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.ORCID https://orcid.org/0000-0002-9024-1056
Robert K NaumannThe Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.ORCID https://orcid.org/0000-0002-1295-9185

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The claustrum is a major connectivity hub for cortical circuits and has recently become a nexus for research on cognition, brain state transitions, and mood disorders. While most recent studies focus on mice, there are ongoing debates regarding the definition of rodent claustrum borders, subregions, development, and constitutive cell types. Hence, problems mount when attempting to compare the claustrum across mammals with diverging brain size and morphology. In particular, understanding the primate claustrum remains challenging, because numerous incongruent parcellation schemes for the primate claustrum exist. Here, we propose that evolutionarily conserved subdivisions of the claustrum complex can be identified across mammals by combining gene expression patterns, cytoarchitecture, and topological position. To this end, we compare selected claustrum-specific genes, such as

Indexed as

claustrumcomparativegene expressionNurr1Oprk1

Identifiers

PMID42345040
PMCPMC13288744

What Socratic holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.