Evidence map›Paper›PMID 42345644›Full record

ArticleAdvances in respiratory medicine2026

Dual E-Cigarette Users Show Nicotine Addiction Risk Alleles and Nuclear Abnormalities in Oral Epithelial Cells.

Oreth Montero-Ruiz, Ramcés Falfán-Valencia, Ivette Buendía-Roldán, Daniela Valencia-Pérez Rea, Gibran E Rueda-Munive, Ingrid Fricke-Galindo, Salvador García-Carmona, Edgar Abarca-Rojano, Gloria Pérez-Rubio

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advances in respiratory medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Oreth Montero-RuizLaboratory of Biochemistry and Neurotoxicology, Faculty of Bioanalysis-Xalapa, Universidad Veracruzana, Médicos y Odontólogos S/N Unidad del Bosque, Xalapa 91010, Mexico.ORCID 0000-0002-2724-5169
Ramcés Falfán-ValenciaPneumogenomics Laboratory, Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Mexico City 14080, Mexico.ORCID 0000-0001-6877-8124
Ivette Buendía-RoldánTranslational Research Clinic on Aging and Pulmonary Fibrosis, Instituto Nacional de Enfermedades Respiratorias Ismael Cosio Villegas, Mexico City 14080, Mexico.ORCID 0000-0002-2825-506X
Daniela Valencia-Pérez ReaPneumogenomics Laboratory, Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Mexico City 14080, Mexico.
Gibran E Rueda-MuniveLaboratory of Biochemistry and Neurotoxicology, Faculty of Bioanalysis-Xalapa, Universidad Veracruzana, Médicos y Odontólogos S/N Unidad del Bosque, Xalapa 91010, Mexico.
Ingrid Fricke-GalindoPneumogenomics Laboratory, Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Mexico City 14080, Mexico.ORCID 0000-0003-2132-1076
Salvador García-CarmonaPneumogenomics Laboratory, Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Mexico City 14080, Mexico.ORCID 0000-0002-5195-7385
Edgar Abarca-RojanoSección de Posgrado e Investigación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Mexico City 11340, Mexico.
Gloria Pérez-RubioPneumogenomics Laboratory, Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Mexico City 14080, Mexico.ORCID 0000-0002-6876-1012

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study was conducted to identify genetic risk variants associated with nicotine addiction in the

methodsWe included dual e-cig users (ECIG,

resultsThe ECIG group demonstrated greater nicotine addiction on the Fagerström Test for Nicotine Dependence (FTND, 5.5 vs. 1,

conclusionsSalivary cotinine levels and FTND are higher in dual e-cigarette users than in combustible cigarette users. Dual users exhibit risk alleles in the

Indexed as

Electronic Nicotine Delivery SystemsEpithelial CellsMouth MucosaTobacco Use DisorderAdultAllelesFemaleHumansMaleMiddle Agedcombustible cigarettedual usere-cigarettegeneticmicronucleismoking

Identifiers

PMID42345644
PMCPMC13295726

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.