Evidence map›Paper›PMID 42345733›Full record

ReviewHematology reports2026

Perioperative Anemia, Transfusion Practices, and Patient Blood Management: Lessons from the COVID-19 Pandemic.

Alin Ionescu, Alexandra Mihăilescu, Raluca Dumache, Alexandru Capcelea, Alexander Dean Turceanu, Nicolae Albulescu, Mihai Alexandru Săndesc

Abstract readReview
In one paragraph

Review in Hematology reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alin IonescuResearch Center in Anesthesia and Intensive Care (CCATITM), "Victor Babeș" University of Medicine and Pharmacy, 300041 Timișoara, Romania.ORCID 0000-0001-9560-5595
Alexandra MihăilescuCentre of Genomic Medicine, Genetics Discipline, "Victor Babeș" University of Medicine and Pharmacy, 300041 Timișoara, Romania.
Raluca DumacheCenter for Ethics in Human Genetic Identifications, "Victor Babeș" University of Medicine and Pharmacy, 300041 Timișoara, Romania.ORCID 0000-0003-1790-8130
Alexandru CapceleaDoctoral School, "Victor Babeș" University of Medicine and Pharmacy, 300041 Timișoara, Romania.ORCID 0009-0005-3781-0335
Alexander Dean TurceanuMedical School, "Victor Babeș" University of Medicine and Pharmacy, 300041 Timișoara, Romania.
Nicolae AlbulescuDepartment of Internal Medicine II, Division of Cardiology, Centre for Molecular Research in Nephrology and Vascular Disease, "Victor Babeș" University of Medicine and Pharmacy, 300041 Timișoara, Romania.
Mihai Alexandru SăndescTeodor Șora Research Center, "Victor Babeș" University of Medicine and Pharmacy, 300041 Timișoara, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The COVID-19 pandemic exposed vulnerabilities in global blood supply systems and accelerated the adoption of patient blood management (PBM) strategies aimed at optimizing transfusion practices in surgical care. Perioperative anemia is a key contributor to adverse outcomes and is frequently treated with allogeneic blood transfusion (ABT), which carries infectious and immunologic risks. Iron deficiency remains the most common and potentially correctable cause of perioperative anemia. This narrative review examines various approaches to perioperative anemia, strategies to minimize reliance on ABT, and alternatives within the PBM paradigm. Evidence supports the use of iron therapy, erythropoiesis-stimulating agents, antifibrinolytic strategies, and blood conservation techniques to reduce transfusion requirements and improve clinical outcomes. Lessons from the COVID-19 pandemic highlight PBM as a framework to enhance transfusion safety and sustainability. Broader implementation of PBM may improve patient outcomes, reduce unnecessary transfusions, and preserve scarce blood resources.

Indexed as

blood transfusionCOVID-19iron deficiencypatient blood managementperioperative anemiatransfusion alternatives

Identifiers

PMID42345733
PMCPMC13299662

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.