Regulation of Neuronal Senescence by

Zhiyu Deng, Jiale Chen, Jing Li, Xiaoman Luo, Qingming Luo, Miao Ren, Xiangning Li

Abstract read

In one paragraph

Article in Biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zhiyu DengKey Laboratory of Biomedical Engineering of Hainan Province, School of Biomedical Engineering, Hainan University, Haikou 570228, China.

Jiale ChenDepartment of Medical 3D Printing Center, The First Affiliated Hospital of Soochow University, Suzhou 215006, China.

Jing LiKey Laboratory of Biomedical Engineering of Hainan Province, School of Biomedical Engineering, Hainan University, Haikou 570228, China.

Xiaoman LuoKey Laboratory of Biomedical Engineering of Hainan Province, School of Biomedical Engineering, Hainan University, Haikou 570228, China.

Qingming LuoKey Laboratory of Biomedical Engineering of Hainan Province, School of Biomedical Engineering, Hainan University, Haikou 570228, China.ORCID 0000-0002-6725-9311

Miao RenKey Laboratory of Biomedical Engineering of Hainan Province, School of Biomedical Engineering, Hainan University, Haikou 570228, China.ORCID 0000-0002-5555-5279

Xiangning LiKey Laboratory of Biomedical Engineering of Hainan Province, School of Biomedical Engineering, Hainan University, Haikou 570228, China.ORCID 0000-0002-3747-2824

Funding

Brain Science and Brain-like Intelligence Technology-National Science and Technology Major Project No. 2021ZD0201004National Natural Science Foundation of China No. 32400931Natural Science Foundation for Scientific and Technological Talents Innovation Programs of Hainan Province KJRC2023A03Natural Science Foundation for Scientific and Technological Talents Innovation Programs of Hainan Province KJRC2023D28Open Project Program of Wuhan National Laboratory for Optoelectronics 2023WNLOKF014

6 · The paper itself

Abstract

Neuronal senescence-like states are increasingly implicated in age-related neurodegeneration, yet the neuron-intrinsic regulators that drive these phenotypes remain poorly defined. Guided by prior transcriptomic analysis of aged basal forebrain cholinergic neurons, we investigated

Indexed as

basal forebrain neuronscholesterol metabolismcholinergic synapseneurodegenerationneuronal senescencetranscriptomic profiling

Identifiers

PMID42345794

DOI10.3390/biology15120938

PMCPMC13295397

What Socratic holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.