Evidence map›Paper›PMID 42346103›Full record

ArticleCells2026

Umbilical Cord Blood Gasometry and pH as Key Regulators of Growth Factor Expression Profile in Umbilical Cord-Derived Mesenchymal Stromal Cells (UC-MSCs).

Dominika Przywara, Wiktor Babiuch, Alicja Petniak, Małgorzata Wasilewska, Jarosław Krzyżanowski, Monika Czuba, Arkadiusz Krzyżanowski, Adrianna Kondracka, Janusz Kocki, Paulina Gil-Kulik

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Dominika PrzywaraDepartment of Clinical Genetics, Medical University of Lublin, 11 Radziwillowska Str., 20-080 Lublin, Poland.ORCID 0000-0002-6143-9653
Wiktor BabiuchStudent Scientific Society of Clinical Genetics, Medical University of Lublin, 20-080 Lublin, Poland.
Alicja PetniakDepartment of Clinical Genetics, Medical University of Lublin, 11 Radziwillowska Str., 20-080 Lublin, Poland.ORCID 0000-0001-9926-0870
Małgorzata WasilewskaDepartment of Physical Chemistry, Institute of Chemical Sciences, Faculty of Chemistry, Maria Curie-Sklodowska University, Maria Curie-Sklodowska Sq. 3, 20-031 Lublin, Poland.ORCID 0000-0001-5747-1178
Jarosław KrzyżanowskiDepartment of Gynecology and Obstetrics, The Independent Public Hospital No. 4, 20-090 Lublin, Poland.ORCID 0000-0002-0018-364X
Monika CzubaDepartment of Clinical Genetics, Medical University of Lublin, 11 Radziwillowska Str., 20-080 Lublin, Poland.
Arkadiusz KrzyżanowskiDepartment of Obstetrics and Pathology of Pregnancy, Medical University of Lublin, 11 Staszica Str., 20-081 Lublin, Poland.
Adrianna KondrackaDepartment of Obstetrics and Pathology of Pregnancy, Medical University of Lublin, 11 Staszica Str., 20-081 Lublin, Poland.
Janusz KockiDepartment of Clinical Genetics, Medical University of Lublin, 11 Radziwillowska Str., 20-080 Lublin, Poland.ORCID 0000-0002-9541-6353
Paulina Gil-KulikDepartment of Clinical Genetics, Medical University of Lublin, 11 Radziwillowska Str., 20-080 Lublin, Poland.ORCID 0000-0003-3119-981X

Funding

Medical University of Lublin DS223
6 · The paper itself

Abstract

Umbilical cord mesenchymal stromal cells (UC-MSCs) are a key element of regenerative medicine due to their ability to secrete growth factors that stimulate proliferation and angiogenesis, and modulate the inflammatory response. Despite their widespread use, the influence of the perinatal microenvironment on their biological properties remains poorly understood. The aim of this study was to assess the influence of pH and blood gas parameters in umbilical cord blood on the global transcriptomic profile of UC-MSCs and to analyze the correlation between the metabolic status of the newborn and the expression of key trophic factors:

Indexed as

Blood Gas AnalysisFetal BloodIntercellular Signaling Peptides and ProteinsMesenchymal Stem CellsUmbilical CordFemaleGene Expression ProfilingHumansHydrogen-Ion ConcentrationInfant, NewbornTranscriptomeIntercellular Signaling Peptides and Proteinscell proliferationneonatal asphyxiaperinatal microenvironmentregenerative medicinetranscriptomicstrophic factorsumbilical cord blood pHumbilical cord mesenchymal stromal cells (UC-MSCs)

Identifiers

PMID42346103
PMCPMC13297315

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.