Evidence map›Paper›PMID 42346804›Full record

ReviewMarine drugs2026

The Potential and Prospects of Marine Drugs in Intervening Nerve-Tumor Crosstalk.

Dan Zhao, Ruiling Xu, Xinyan Xu, Jingxuan Tan, Zhili Zeng, Xirenayi Kanji, Xincan Li, Junchi Hu, Shuai Wang, Yongjun Dang

Abstract readReview
In one paragraph

Review in Marine drugs, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Dan ZhaoBasic Medicine Research and Innovation Center for Novel Target and Therapeutic Intervention, College of Pharmacy, Chongqing Medical University, Ministry of Education, Chongqing 400016, China.
Ruiling XuThe First Clinical College, Chongqing Medical University, Chongqing 400016, China.
Xinyan XuThe First Clinical College, Chongqing Medical University, Chongqing 400016, China.ORCID 0009-0003-3527-890X
Jingxuan TanThe First Clinical College, Chongqing Medical University, Chongqing 400016, China.
Zhili ZengCollege of Pharmacy, Chongqing Medical University, Chongqing 400016, China.
Xirenayi KanjiCollege of Pharmacy, Chongqing Medical University, Chongqing 400016, China.
Xincan LiCollege of Pharmacy, Chongqing Medical University, Chongqing 400016, China.
Junchi HuBasic Medicine Research and Innovation Center for Novel Target and Therapeutic Intervention, College of Pharmacy, Chongqing Medical University, Ministry of Education, Chongqing 400016, China.
Shuai WangBasic Medicine Research and Innovation Center for Novel Target and Therapeutic Intervention, College of Pharmacy, Chongqing Medical University, Ministry of Education, Chongqing 400016, China.ORCID 0000-0002-2394-1650
Yongjun DangBasic Medicine Research and Innovation Center for Novel Target and Therapeutic Intervention, College of Pharmacy, Chongqing Medical University, Ministry of Education, Chongqing 400016, China.

Funding

National Natural Science Foundation of China 82204269the National Key R&D Program of China 2024YFC2815900
6 · The paper itself

Abstract

The bidirectional crosstalk between the nervous system and tumors has emerged as a transformative new frontier in both precision oncotherapy and mechanism-driven cancer pain management. Marine natural products with inherent neuroactive properties exhibit unparalleled intervention advantages for targeting this complex pathophysiological axis. Herein, we systematically and prospectively dissect the multi-layered bidirectional communication between the nervous system and malignancies, comprehensively summarize the pivotal contributions of marine-derived bioactive molecules to advances in neuroscience and antitumor therapeutics, and finally provide an outlook on and a call for integrated, interdisciplinary collaboration to enable transformative breakthroughs in the development of marine neuropharmacological agents targeting the nerve-tumor crosstalk axis.

Indexed as

Antineoplastic AgentsAquatic OrganismsBiological ProductsNeoplasmsAnimalsCancer PainHumansAntineoplastic AgentsBiological Productscancer painmarine drugsnerve–tumor crosstalkoncotherapy

Identifiers

PMID42346804
PMCPMC13301399

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.