Evidence map›Paper›PMID 42346805›Full record

Trial reportMarine drugs2026

Seaweed-Derived Extract Targets Porphyr'ageing to Modulate the Visible Signs of Aging in Human Skin.

Morgane De Tollenaere, Marie Meunier, Emilie Chapuis, Marine Bracq, Cyrille Jarrin, Perrine Lemagnen, Patrick Robe, Laura Lapierre, Jean Tiguemounine, Catherine Zanchetta and 7 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Marine drugs, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Morgane De TollenaereGivaudan Active Beauty, Research and Development, Givaudan France SAS, 95018 Argenteuil, France.ORCID 0000-0001-8283-7864
Marie MeunierGivaudan Active Beauty, Research and Development, Givaudan France SAS, 95018 Argenteuil, France.ORCID 0000-0003-2925-9094
Emilie ChapuisGivaudan Active Beauty, Research and Development, Givaudan France SAS, 95018 Argenteuil, France.
Marine BracqGivaudan Active Beauty, Research and Development, Givaudan France SAS, 95018 Argenteuil, France.
Cyrille JarrinGivaudan Active Beauty, Research and Development, Givaudan France SAS, 95018 Argenteuil, France.ORCID 0000-0001-9968-4227
Perrine LemagnenGivaudan Active Beauty, Research and Development, Givaudan France SAS, 95018 Argenteuil, France.
Patrick RobeGivaudan Active Beauty, Research and Development, Givaudan France SAS, 95018 Argenteuil, France.ORCID 0000-0002-9102-7801
Laura LapierreGivaudan Active Beauty, Research and Development, Givaudan France SAS, 95018 Argenteuil, France.
Jean TiguemouninePlastic Surgery, Polyclinique Courlancy, 51100 Reims, France.
Catherine ZanchettaGivaudan Active Beauty, Research and Development, Givaudan France SAS, 95018 Argenteuil, France.ORCID 0000-0002-7307-3097
Anne HumeauGivaudan Active Beauty, Research and Development, Givaudan France SAS, 95018 Argenteuil, France.
Aurélie PréchouxALGAIA R&D Center, 50000 Saint-Lô, France.
Jeremy BrebionALGAIA R&D Center, 50000 Saint-Lô, France.
Franck HennequartALGAIA R&D Center, 50000 Saint-Lô, France.
Maud BenoitALGAIA R&D Center, 50000 Saint-Lô, France.
Amandine ScandoleraGivaudan Active Beauty, Research and Development, Givaudan France SAS, 95018 Argenteuil, France.ORCID 0000-0001-6403-1664
Romain ReynaudGivaudan Active Beauty, Research and Development, Givaudan France SAS, 95018 Argenteuil, France.ORCID 0000-0001-5417-5357

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent evidence suggests that microbiota-derived porphyrins contribute to skin aging, a phenomenon termed porphyr'aging. These pro-inflammatory molecules alter the expression of genes involved in senescence, trigger melanogenesis, and decrease collagen I synthesis in skin. The aim of this study was to evaluate the anti-aging properties of an upcycled

Indexed as

LaminariaPlant ExtractsSeaweedSkin AgingAdultCollagen Type IDouble-Blind MethodFemaleFibroblastsHumansMaleMelaninsMiddle AgedPorphyrinsSkinCollagen Type IMelaninsPlant ExtractsPorphyrinscollagencoproporphyrinelastinlaminaranlaminarinmelaninpigmentationwrinkle

Identifiers

PMID42346805
PMCPMC13301944

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.