Evidence map›Paper›PMID 42348089›Full record

ArticleEuropean journal of epidemiology2026

Wqsreg: a Stata command for weighted quantile sum regression.

Marta Ponzano, Stefano Renzetti, Chris Gennings, Andrea Bellavia

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Article in European journal of epidemiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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5 · Who and what money

Authors and funding

4 authors.

Marta PonzanoDepartment of Life Sciences, Health and Health Professions, Link Campus University, Rome, Italy.
Stefano RenzettiDepartment of Medicine and Surgery, University of Parma, Parma, Italy.
Chris GenningsDepartment of Environmental Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Andrea BellaviaDepartment of Environmental Health, Harvard T.H. Chan School of Public Health Boston, Boston, MA, USA. abellavia@bwh.harvard.edu.ORCID http://orcid.org/0000-0003-4988-4532

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Weighted Quantile Sum (WQS) regression is a statistical method for quantifying the association between multiple possibly correlated predictors and a health outcome, estimating both the joint effect of the predictors as well as their individual contributions to the total effect. WQS has become one of the most popular and widely used approaches for investigating complex mixtures in environmental epidemiology, yet its implementation has been largely restricted to R users. In this paper we present wqsreg, the first Stata command for WQS regression, implemented for continuous, binary and count outcomes. We describe command's architecture and present an application of the command on exposome data exploring the association between 38 exposures and a continuous outcome. Wqsreg provides a user-friendly command for WQS regression that integrates several flexible components of the framework such as bootstrap, training/validation splitting, and repeated holdout procedures. Wqsreg returns regression estimates as well as graphical displays of the individual weights. It requires Stata version 11 or higher and is freely available on GitHub [ https://github.com/PonzanoMarta/wqsreg ]. Given the increasing importance of appropriately exploring complex multidimensional exposures, this contribution will further promote the use of appropriate statistical methods in epidemiological settings with multiple correlated predictors.

Indexed as

Environmental ExposureModels, StatisticalSoftwareExposomeHumansRegression AnalysisBiomarkersCorrelated predictorsEnvironmental mixturesSoftwareStata

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.