Evidence map›Paper›PMID 42348466›Full record

ReviewDermatology (Basel, Switzerland)2026

Mpox Outbreaks Beyond Historically Endemic Regions: A Clinical Review of Vaccination Strategies and Public Health Challenges.

Goranit Sakunchotpanit, Ryan Chen, Laura I Ortiz López, Maya Akbik, Vinod E Nambudiri

Abstract readReview
In one paragraph

Review in Dermatology (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Goranit SakunchotpanitDepartment of Dermatology, Brigham and Women's Hospital, Boston, Massachusetts, USA, cjsakunchotpanit@gmail.com.
Ryan ChenDepartment of Dermatology, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Laura I Ortiz LópezDepartment of Dermatology, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Maya AkbikDepartment of Dermatology, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Vinod E NambudiriDepartment of Dermatology, Brigham and Women's Hospital, Boston, Massachusetts, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMpox, caused by the monkeypox virus, emerged as a global public health concern following the 2022 outbreaks in non-endemic regions. Although classical presentations include a febrile prodrome and mucocutaneous lesions, atypical symptoms and stigma have complicated clinical recognition and containment. Smallpox-derived vaccines, such as ACAM2000 and modified vaccinia Ankara, have been deployed for prophylaxis; however, access, policy implementation, and public acceptance remain inconsistent across regions. SUMMARY: Global mpox vaccination strategies demonstrate pronounced disparities in coverage, infrastructure, and public trust. High-income countries, including the USA and European nations, prioritized men who have sex with men, transgender individuals, and people living with human immunodeficiency virus through targeted outreach in sexual health clinics and community-based programs. In contrast, many Southeast Asian and African nations lacked coordinated vaccination campaigns due to limited resources, weak surveillance systems, and low awareness. Misinformation and sociocultural stigma further suppressed vaccine uptake, particularly in parts of the Eastern Mediterranean region. In settings such as Taiwan and the Netherlands, inclusive public health messaging and equitable access policies contributed to higher vaccination coverage. Healthcare worker knowledge significantly influenced vaccine delivery, though educational gaps persist. KEY MESSAGES: Despite demonstrated efficacy, vaccination coverage remains globally inequitable, with disparities shaped by structural and social determinants, including race, socioeconomic status, and geography. Dermatologists play a pivotal role in early detection, patient counseling, and vaccine advocacy. Strengthening coordinated, evidence-based vaccination strategies is essential to improving outbreak preparedness and advancing global health equity.

Indexed as

Global healthMpoxPublic health policyVaccinationZoonotic disease

Identifiers

PMID42348466
PMCPMC13446878

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.