ArticleAntonie van Leeuwenhoek2026
Antimicrobial efficacy of cyanobacterium Synechococcus pevalekii extracts against MDR bacteria and fungi; an integrated GC-MS, molecular docking and MD simulation study.
Article in Antonie van Leeuwenhoek, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
8 authors.
Funding
Abstract
This study evaluates the antimicrobial properties of marine unicellular cyanobacterium Synechococcus pevalekii using integrated in vitro and in silico approach. Solvents including methanol, ethanol, ethyl acetate, butanol and acetone were used for biomass extraction and were assessed against a collection of pathogens, such as Staphylococcus aureus, Streptococcus pyogenes, Klebsiella pneumoniae, Escherichia coli, Candida tropicalis, and Trichophyton rubrum. The butanol and ethyl acetate extracts emerged as the most potent; the butanol extract exhibited a maximum ZOI of 22 mm against E. coli, while the ethyl acetate extract reached 20 mm against K. pneumoniae. Both extracts had low MIC of 1.56 mg/mL. In terms of antioxidant activity, the methanol extract was the most active with IC
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Registered trials
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