Evidence map›Paper›PMID 42350866›Full record

SynthesisBiological trace element research2026

Addition of Selenium to Silver Nanoparticles: An Approach to Enhance Their Antimicrobial and Biological Properties - Systematic Review.

João Marcos Carvalho-Silva, Andréa Cândido Dos Reis

Abstract readSystematic Review
In one paragraph

Synthesis in Biological trace element research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

João Marcos Carvalho-SilvaDepartment of Dental Materials and Prosthesis, Ribeirão Preto School of Dentistry, University of São Paulo (USP), Avenida Do Café, s/n, Ribeirão Preto, São Paulo, 14040-904, Brazil.
Andréa Cândido Dos ReisDepartment of Dental Materials and Prosthesis, Ribeirão Preto School of Dentistry, University of São Paulo (USP), Avenida Do Café, s/n, Ribeirão Preto, São Paulo, 14040-904, Brazil. andreare73@yahoo.com.br.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim was to address the question, "Can the addition of selenium nanoparticles (SeNPs) to silver nanoparticles (AgNPs) enhance their antimicrobial and biological properties?" This systematic review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 guidelines and was registered in the Open Science Framework (OSF). A comprehensive search was conducted in Scopus, PubMed, Embase, Lilacs, ScienceDirect, and the gray literature databases (Google Scholar and ProQuest) to identify in vitro studies evaluating the effect of SeNPs incorporation into AgNPs (Se-AgNPs) on antimicrobial activity and biological behavior. Se-AgNPs demonstrated enhanced antimicrobial and antibiofilm activity against both Gram-positive and Gram-negative bacteria, as well as fungal strains. Additionally, they exhibited improved cell adhesion, viability, and proliferation, along with reduced cytotoxicity. Se-AgNPs showed a synergistic enhancement of antimicrobial and antibiofilm activity, with a potential reduction in cytotoxic effects. Nevertheless, the small number of studies limits the strength of the conclusions, underscoring the need for rigorous, standardized investigations to strengthen or refute these findings.

Indexed as

Anti-Bacterial AgentsMetal NanoparticlesSeleniumSilverAnimalsAnti-Infective AgentsBiofilmsGram-Negative BacteriaGram-Positive BacteriaHumansMicrobial Sensitivity TestsAnti-Bacterial AgentsAnti-Infective AgentsSeleniumSilverAntimicrobialCytotoxicityNanomedicineNanoparticlesSeleniumSilver

Identifiers

PMID42350866
PMCPMC13437565

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.