Evidence map›Paper›PMID 42351825›Full record

ReviewBiomedicines2026

Intravascular Imaging Versus Physiology Assessment for Intermediate Lesions During PCI.

Marios Sagris, Athanasios Makris, Svetlana Aghayan, Stergios Soulaidopoulos, Alexios Giannakodimos, Konstantinos Platanias, Andreas Tzoumas, Nikolaos Ktenopoulos, Konstantinos Pamporis, Nikolaos Stalikas and 5 more

Abstract readReview
In one paragraph

Review in Biomedicines, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Marios SagrisSchool of Medicine, Hippokration General Hospital, National and Kapodistrian University of Athens, 106 79 Athens, Greece.ORCID 0000-0002-3473-1368
Athanasios MakrisSchool of Medicine, Hippokration General Hospital, National and Kapodistrian University of Athens, 106 79 Athens, Greece.ORCID 0009-0000-0313-7473
Svetlana AghayanSchool of Medicine, Hippokration General Hospital, National and Kapodistrian University of Athens, 106 79 Athens, Greece.ORCID 0009-0007-3058-8000
Stergios SoulaidopoulosSchool of Medicine, Hippokration General Hospital, National and Kapodistrian University of Athens, 106 79 Athens, Greece.
Alexios GiannakodimosDepartment of Cardiology, "Tzaneio" General Hospital of Piraeus, 185 36 Piraeus, Greece.ORCID 0000-0003-0570-8510
Konstantinos PlataniasSchool of Medicine, Hippokration General Hospital, National and Kapodistrian University of Athens, 106 79 Athens, Greece.
Andreas TzoumasDivision of Cardiovascular Health and Disease, University of Cincinnati Medical Center, Cincinnati, OH 45219, USA.ORCID 0000-0002-7903-6975
Nikolaos KtenopoulosSchool of Medicine, Hippokration General Hospital, National and Kapodistrian University of Athens, 106 79 Athens, Greece.ORCID 0000-0002-0995-7015
Konstantinos PamporisDepartment of Hygiene, Social-Preventive Medicine & Medical Statistics, Medical School, Aristotle University of Thessaloniki, 541 24 Thessaloniki, Greece.ORCID 0000-0001-5411-6461
Nikolaos StalikasCardiovascular Center Aalst, AZORG Hospital, 9300 Aalst, Belgium.ORCID 0000-0002-0190-5392
Gerasimos GavrielatosDepartment of Cardiology, "Tzaneio" General Hospital of Piraeus, 185 36 Piraeus, Greece.ORCID 0000-0003-3491-6968
Efstratios KaragiannidisDepartment of Emergency Medicine, AHEPA University Hospital, 54 636 Thessaloniki, Greece.ORCID 0000-0001-8328-5942
Nikolaos PatsourakosDepartment of Cardiology, "Tzaneio" General Hospital of Piraeus, 185 36 Piraeus, Greece.ORCID 0000-0001-5198-6314
Dimitris TousoulisSchool of Medicine, Hippokration General Hospital, National and Kapodistrian University of Athens, 106 79 Athens, Greece.
Konstantinos TsioufisSchool of Medicine, Hippokration General Hospital, National and Kapodistrian University of Athens, 106 79 Athens, Greece.ORCID 0000-0002-7636-6725

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronary artery disease (CAD) is the leading cause of mortality, with percutaneous coronary intervention (PCI) constituting the gold standard treatment. However, in an important proportion of the cases, lesion severity is debatable since conventional angiography provides only a two-dimensional representation of the vessel lumen and fails to quantify ischemic significance or plaque morphology. In these cases, several adjunctive tools considering physiology and imaging guidance may assist in quantifying the severity of the disease. Imaging modalities such as intravascular ultrasonography (IVUS) and optical coherence tomography (OCT), as well as physiology such as fractional flow reserve (FFR) and instantaneous wave-free (iFR), revolutionized revascularization strategy by linking anatomical stenosis to its functional consequence on myocardial perfusion. The present review summarizes and contrasts the available evidence for physiology and imaging guidance, considering the assessment of intermediate lesions during PCI and providing insights for their use in specific lesion subsets.

Indexed as

FFRiFRintermediate lesionsintravascular imagingIVUSOCTPCIphysiology

Identifiers

PMID42351825
PMCPMC13297278

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.