Evidence mapPaperPMID 42352246Full record

ReviewBiomolecules2026

AP1 Transcription Factor in the Regulation of the Urokinase Plasminogen Activation System.

Petra Korać, Mariastefania Antica, Maja Matulić

Abstract readReview
In one paragraph

Review in Biomolecules, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Petra KoraćFaculty of Science, University of Zagreb, Horvatovac 102, 10000 Zagreb, Croatia.ORCID 0000-0003-4783-2114
Mariastefania AnticaFaculty of Science, University of Zagreb, Horvatovac 102, 10000 Zagreb, Croatia.ORCID 0000-0001-8449-1078
Maja MatulićFaculty of Science, University of Zagreb, Horvatovac 102, 10000 Zagreb, Croatia.ORCID 0000-0002-3498-5616

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Urokinase plasminogen activation system regulates the activation of plasminogen to produce the ubiquitous extracellular protease plasmin. It is involved in different physiological and pathophysiological processes, which involve tissue reorganization, wound healing, cell migration and invasion, etc. The system comprises urokinase plasminogen activator, an extracellular protease, its inhibitor plasminogen activator inhibitor PAI1 and urokinase receptor, uPAR. The system is regulated at the level of transcription and posttranscriptionally, and the net urokinase activity depends on the balance between urokinase and PAI1. Promoters of

Indexed as

Transcription Factor AP-1Urokinase-Type Plasminogen ActivatorAnimalsGene Expression RegulationHumansPlasminogen Activator Inhibitor 1Promoter Regions, GeneticReceptors, Urokinase Plasminogen ActivatorSignal TransductionPlasminogen Activator Inhibitor 1Receptors, Urokinase Plasminogen ActivatorTranscription Factor AP-1Urokinase-Type Plasminogen ActivatorAP1PAI1promoterurokinase plasminogen activatorurokinase plasminogen activator receptor

Identifiers

PMID42352246
PMCPMC13297097

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.