ReviewCancers2026
Small Extracellular Vesicle-Associated microRNA in Cancer: Biology and Applications in Translational Research and Precision Oncology.
Review in Cancers, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Small extracellular vesicles (sEVs) are extracellular vesicles that mediate intercellular communication through the transfer of bioactive molecules, including proteins, lipids, and nucleic acids. Among their cargo, microRNAs (miRNAs) have emerged as critical regulators of gene expression with significant implications in cancer biology. Tumor-derived extracellular vesicle-associated microRNAs (EV-miRNAs) can reprogram recipient cells, promoting oncogenesis, metastasis, angiogenesis, and therapeutic resistance. This review provides a comprehensive overview of EV-miRNAs in cancer, examining their biogenesis, mechanisms of intercellular transfer, and functional roles in tumor progression. We discuss the clinical potential of EV-miRNAs as non-invasive biomarkers for cancer diagnosis and prognosis, as well as their emerging applications in targeted therapeutic strategies. Furthermore, we address current challenges related to isolation techniques, quantification methods, and standardization protocols that hinder clinical translation. Finally, we outline future directions for integrating EV-miRNA analysis into precision oncology frameworks and liquid biopsy platforms, highlighting opportunities to advance personalized cancer care.
Indexed as
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.