ReviewInternational journal of molecular sciences2026
Exploring the Therapeutic Potential of Lycopene: Mechanisms, Biological Activities, and Health Benefits.
Review in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Syringic Acid in Health and Disease: Mechanisms, Biological Activities, and Future Perspectives.International journal of molecular sciences · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lycopene, a carotenoid commonly found in tomatoes, is an emerging compound with a noteworthy role in the prevention and treatment of various pathologies. Evidence from in vitro and in vivo models indicates that lycopene plays an imperative role in disease management through the regulation of oxidative stress, inflammation, and the modulation of various biological processes. Its role containing nephroprotective, hepatoprotective, cardioprotective, and neuroprotective properties, anti-arthritis, anti-obesity, and wound healing has been documented. Its significant role in cancer management through modulation of inflammation, angiogenesis, apoptosis, cell cycle, and PI3/Akt pathways has been properly described. This review aims to provide a comprehensive overview of the role of lycopene in the management of pathogenesis. The review further evaluates the current evidence regarding the synergistic interactions of lycopene with other bioactive compounds and drugs and highlights the potential of emerging nanoformulation strategies to improve its bioavailability and therapeutic efficacy in disease management. However, this compound shows some limitations, particularly its low bioavailability and poor water solubility, which hinder its therapeutic benefit in disease management. For a better understanding of its mechanisms of action, safety considerations, potential drug interactions, and optimal dosages, further detailed studies based on both preclinical and clinical data are needed. This further investigation is essential to reveal the maximum potential benefit of lycopene in disease management.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.