Evidence mapPaperPMID 42353141Full record

ArticleInternational journal of molecular sciences2026

Pulmonary Immune Cell Landscape Altered by Exposure to HIV,

Daniel Morales-Cano, Sandra Medrano-Garcia, Bianca Barreira, Ana Hernández-García, Rahul Kumar, Brian B Graham, Rajkumar Savai, Soni Savai Pullamsetti, Francisco Perez-Vizcaino, Ghazwan Butrous and 2 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Daniel Morales-CanoDepartment of Pharmacology and Toxicology, School of Medicine, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria Gregorio Marañón, 28040 Madrid, Spain.ORCID 0000-0002-1692-4633
Sandra Medrano-GarciaDepartment of Immunology, Ophthalmology and ENT, School of Medicine, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria Hospital 12 de Octubre (imas12), 28040 Madrid, Spain.ORCID 0000-0003-2802-2327
Bianca BarreiraDepartment of Pharmacology and Toxicology, School of Medicine, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria Gregorio Marañón, 28040 Madrid, Spain.
Ana Hernández-GarcíaDepartment of Pharmacology and Toxicology, School of Medicine, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria Gregorio Marañón, 28040 Madrid, Spain.ORCID 0009-0001-2005-7077
Rahul KumarDepartment of Translational Immunology, Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
Brian B GrahamDepartment of Medicine, University of California, San Francisco, CA 94143, USA.ORCID 0000-0001-7541-2585
Rajkumar SavaiInstitute for Lung Health (ILH), Justus Liebig University, 35305 Giessen, Germany.ORCID 0000-0003-1538-2091
Soni Savai PullamsettiInstitute for Lung Health (ILH), Justus Liebig University, 35305 Giessen, Germany.ORCID 0000-0003-0440-8831
Francisco Perez-VizcainoDepartment of Pharmacology and Toxicology, School of Medicine, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria Gregorio Marañón, 28040 Madrid, Spain.ORCID 0000-0001-6309-7418
Ghazwan ButrousCardiopulmonary Sciences, University of Kent Canterbury, Kent CT2 7NZ, UK.ORCID 0000-0002-6640-6332
Angel CogolludoDepartment of Pharmacology and Toxicology, School of Medicine, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria Gregorio Marañón, 28040 Madrid, Spain.ORCID 0000-0002-1382-1698
Edgar Fernández-MalavéDepartment of Immunology, Ophthalmology and ENT, School of Medicine, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria Hospital 12 de Octubre (imas12), 28040 Madrid, Spain.ORCID 0000-0003-3662-8505

Funding

Ministerio de Ciencia, Innovación y Universidades PID2020-117939RB-I00
6 · The paper itself

Abstract

Local immune cell activation and vascular remodelling are characteristic pathogenic features of pulmonary arterial hypertension (PAH). HIV and schistosome infections have been individually associated with PAH. However, whether co-infection with these pathogens has a distinct impact on the development of pulmonary vascular disease remains poorly understood, partly due to the lack of experimental animal models. In a novel non-infectious model of HIV and

Indexed as

CoinfectionHIV InfectionsLungSchistosomaSchistosomiasisAnimalsDisease Models, AnimalFemaleHumansHypertension, PulmonaryMiceMice, TransgenicSchistosoma mansoniHIV proteinsimmune cellslungspulmonary arterial hypertensionSchistosoma

Identifiers

PMID42353141
PMCPMC13300048

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.