Evidence mapPaperPMID 42353182Full record

ReviewInternational journal of molecular sciences2026

Dysregulation of the Tau-Microtubule-End-Binding Protein Axis in Alzheimer's Disease and Related Tauopathies.

Mahmudul Hasan, Kholoud Abd-ElRaouf, Sophia R Moran, Chih Hung Lo

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mahmudul HasanDepartment of Biology, Syracuse University, Syracuse, NY 13244, USA.
Kholoud Abd-ElRaoufDepartment of Biology, Syracuse University, Syracuse, NY 13244, USA.
Sophia R MoranDepartment of Biology, Syracuse University, Syracuse, NY 13244, USA.
Chih Hung LoDepartment of Biology, Syracuse University, Syracuse, NY 13244, USA.ORCID 0000-0003-2717-4484

Funding

Syracuse University Start-up fund
6 · The paper itself

Abstract

Alzheimer's disease (AD) and related tauopathies are marked by progressive cognitive decline, synaptic dysfunction, and neuronal loss. The microtubule (MT)-associated protein tau, encoded by the

Indexed as

Alzheimer DiseaseMicrotubule-Associated ProteinsMicrotubulesTauopathiestau ProteinsAnimalsHumansMicrotubule-Associated Proteinstau ProteinsAlzheimer’s diseasecytoskeletonend-binding proteinshyperphosphorylationliquid-liquid phase separationmicrotubule stabilityneurodegenerative disorderstau aggregationtau oligomerizationtherapeutic strategy

Identifiers

PMID42353182
PMCPMC13300663

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.