Evidence map›Paper›PMID 42353333›Full record

ArticleInternational journal of molecular sciences2026

Aortic Single-Cell Transcriptome Analysis Reveals ApoE-Isoform-Specific Influences on Vascular Disease.

David Y Hui, Jeyashree Alagarsamy, April Haller, Mario Medvedovic, Anja Jaeschke

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

David Y HuiDepartment of Pathology and Laboratory Medicine, University of Cincinnati College of Medicine, Cincinnati, OH 45237, USA.ORCID 0000-0001-7333-2151
Jeyashree AlagarsamyDepartment of Pathology and Laboratory Medicine, University of Cincinnati College of Medicine, Cincinnati, OH 45237, USA.
April HallerDepartment of Pathology and Laboratory Medicine, University of Cincinnati College of Medicine, Cincinnati, OH 45237, USA.ORCID 0000-0002-0560-3033
Mario MedvedovicDepartment of Biostatistics, Health Informatics, and Data Sciences, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA.
Anja JaeschkeDepartment of Pathology and Laboratory Medicine, University of Cincinnati College of Medicine, Cincinnati, OH 45237, USA.

Funding

National Heart Lung and Blood Institute RO1HL156954
6 · The paper itself

Abstract

The human

Indexed as

AortaApolipoproteins EAtherosclerosisTranscriptomeVascular DiseasesAnimalsApolipoprotein E2Apolipoprotein E3Apolipoprotein E4Diet, High-FatGene Expression ProfilingHumansHyperlipidemiasInflammationMaleMiceApolipoprotein E2Apolipoprotein E3Apolipoprotein E4Apolipoproteins EProtein Isoformsapolipoprotein Eatherosclerosisinflammationintracellular lipid accumulationsingle-cell transcriptome

Identifiers

PMID42353333
PMCPMC13299737

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.