Evidence map›Paper›PMID 42354124›Full record

ReviewFoods (Basel, Switzerland)2026

Advances in Enzymatic Production of Prebiotic Oligosaccharides from Agro-Industrial Waste: A Critical Review and Industrial Framework.

Slim Smaoui

Abstract readReview
In one paragraph

Review in Foods (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Slim SmaouiLaboratory of Microbial and Enzymes Biotechnology and Biomolecules (LMEBB), Centre of Biotechnology of Sfax (CBS), University of Sfax-Tunisia, Road of Sidi Mansour Km 6, P.O. Box 1177, Sfax 3018, Tunisia.ORCID 0000-0002-8839-7377

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Agro-industrial wastes are abundant, low-cost feedstocks used for the sustainable production of prebiotic oligosaccharides via enzymatic methods. This review summarizes recent advances, with particular emphasis on studies published after 2020, in the enzymatic valorization of these by-products, highlighting pretreatment strategies, enzyme classifications, and reaction conditions for converting complex substrates into functional prebiotic ingredients. In parallel, pioneering studies are recognized as foundational work, as they offer key mechanistic insights and continue to play a key role in supporting the interpretation of recent advances in the field. The functionality of the resulting prebiotic oligosaccharides, assessed through various in vitro models, is discussed, with emphasis on their impact on the technological performance of different food matrices. Evidence from in vitro and human studies further illustrates the biological activity and added value of waste-derived prebiotic oligosaccharides. While enzymatic technologies demonstrate high efficiency and selectivity, the full potential of many agro-industrial wastes for bioconversion remains underexplored. Optimizing enzymatic processes and systematically assessing functionality are essential in order to fully harness these resources, supporting the development of innovative, value-added food products within a circular bioeconomy. This review provides an integrated platform linking prebiotic oligosaccharide production, functionality, and food applications, promoting the valorization of agro-industrial waste into high-value prebiotic ingredients.

Indexed as

agro-industrial wastefood applicationmicrobial fermentationprebiotic oligosaccharides

Identifiers

PMID42354124
PMCPMC13298954

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.