Evidence map›Paper›PMID 42354161›Full record

ReviewFoods (Basel, Switzerland)2026

From Brewing By-Products to Next-Generation Food Ingredients: Processing, Functionality, Safety, and Industrial Translation.

Ionut-Dumitru Veleșcu, Ioana Cristina Crivei, Andreea Bianca Balint, Florina Stoica, Florin Daniel Lipșa, Roxana Nicoleta Rațu

Abstract readReview
In one paragraph

Review in Foods (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ionut-Dumitru VeleșcuFaculty of Agriculture, Department of Food Technologies, "Ion Ionescu de la Brad" Iasi University of Life Sciences, 3 Mihail Sadoveanu Alley, 700489 Iasi, Romania.ORCID 0009-0009-2313-0063
Ioana Cristina CriveiFaculty of Agriculture, Department of Food Technologies, "Ion Ionescu de la Brad" Iasi University of Life Sciences, 3 Mihail Sadoveanu Alley, 700489 Iasi, Romania.ORCID 0000-0002-3048-5761
Andreea Bianca BalintFaculty of Agriculture, Department of Food Technologies, "Ion Ionescu de la Brad" Iasi University of Life Sciences, 3 Mihail Sadoveanu Alley, 700489 Iasi, Romania.
Florina StoicaFaculty of Agriculture, Department of Pedotechnics, "Ion Ionescu de la Brad" Iasi University of Life Sciences, 3 Mihail Sadoveanu Alley, 700489 Iasi, Romania.
Florin Daniel LipșaFaculty of Agriculture, Department of Food Technologies, "Ion Ionescu de la Brad" Iasi University of Life Sciences, 3 Mihail Sadoveanu Alley, 700489 Iasi, Romania.ORCID 0000-0002-2127-4225
Roxana Nicoleta RațuFaculty of Agriculture, Department of Food Technologies, "Ion Ionescu de la Brad" Iasi University of Life Sciences, 3 Mihail Sadoveanu Alley, 700489 Iasi, Romania.ORCID 0000-0001-5637-4376

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Brewing generates several by-products with high potential for conversion into food in-gredients, including brewer's spent grain, brewer's spent yeast, spent hops, and hot trub. These streams contain dietary fibre, proteins, β-glucans, phenolics, minerals, and others with nutritional and technological value. This review evaluates their suitability for food applications by linking composition, processing routes, techno-functional behaviour, safety, sensory quality, and industrial readiness. A structured literature search covering publications from 2015 to 2026 was conducted in Web of Science, Scopus, PubMed, and Google Scholar to support a critical narrative synthesis of food-relevant applications of brewing by-products. The review shows that brewer's spent grain is the most suitable by-product for wider food use, mainly in bakery, snacks, pasta, and cereal-based products, due to its high availability and fibre-rich composition. Brewer's spent yeast is more appropriate for fraction-based applications involving proteins, peptides, β-glucans, and mannoproteins, especially in dairy products, savoury foods, beverages, and encapsula-tion systems. Spent hops and hot trub are less suitable for direct incorporation, but they may be used for selective recovery of phenolic-rich, antioxidant, flavour-active, or pro-tein-containing fractions. The conversion of these materials into food ingredients depends strongly on stabilization, drying, milling, extraction, fermentation, enzymatic treatment, debittering, and fractionation. Main limitations include high moisture content, short shelf-life, microbial spoilage, compositional variability, bitterness, dark colour, high nucleic acid content in yeast-derived fractions, regulatory uncertainty, and limited pilot-scale validation. Overall, brewing by-products can support the development of up-cycled ingredients when processing, safety, sensory quality, and product compatibility are controlled. Future progress requires standardized recovery protocols, stronger quality control, sensory validation, legal assessment, and scale-up studies to support their use in commercial food production.

Indexed as

brewing by-productsfood ingredientsfood safetytechno-functional propertiesupcycled food

Identifiers

PMID42354161
PMCPMC13298281

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.