ArticleMaterials (Basel, Switzerland)2026
Sintering Method-Dependent Hydroxyapatite Coatings Drive Enhanced Gingival Fibroblast Behavior on Titanium Implant Surfaces.
Article in Materials (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Implant surface optimization aims to reduce osteointegration process time and prevent failures. Here, we report a novel laser-assisted approach for incorporating hydroxyapatite into titanium implant surfaces and evaluate the resulting biological response. Titanium discs were fabricated by Nd:YVO4 laser texturing and coated with hydroxyapatite using either conventional or laser sintering, according to seven study groups: flat titanium (TiL), laser-textured titanium with 0.25 and 0.8 mm patterns (TiT025 and TiT08), and laser-textured titanium with 0.25 and 0.8 mm patterns plus bioactive coating using conventional sintering (TiT025CS and TiT08CS) or laser sintering (TiT025LS and TiT08LS). Human gingival fibroblasts (HGF hTERT) were cultured on discs to assess adhesion, morphology, viability, and cytokine secretion. Surface texturing alone did not significantly affect fibroblast viability over 7 days (
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