Evidence map›Paper›PMID 42355396›Full record

ArticleLife (Basel, Switzerland)2026

Identification and Functional Characterization of a Novel POU3F4 Frameshift Mutation in a Chinese Family.

Shuwen Fan, Yaqiong Guan, Mengya Xiang, Hongzhe Yu, Tianyang Zhang, Jialei Fu, Jiahao Fei, Yongtao Xiao, Yunfeng Wang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Life (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Shuwen FanENT Institute, Department of Otorhinolaryngology, EYE & ENT Hospital, Fudan University, Shanghai 200031, China.
Yaqiong GuanDepartment of Medical Technology and Information Engineering, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Mengya XiangENT Institute, Department of Otorhinolaryngology, EYE & ENT Hospital, Fudan University, Shanghai 200031, China.
Hongzhe YuENT Institute, Department of Otorhinolaryngology, EYE & ENT Hospital, Fudan University, Shanghai 200031, China.
Tianyang ZhangENT Institute, Department of Otorhinolaryngology, EYE & ENT Hospital, Fudan University, Shanghai 200031, China.
Jialei FuENT Institute, Department of Otorhinolaryngology, EYE & ENT Hospital, Fudan University, Shanghai 200031, China.
Jiahao FeiDepartment of Medical Technology and Information Engineering, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Yongtao XiaoDepartment of Medical Technology and Information Engineering, Zhejiang Chinese Medical University, Hangzhou 310053, China.ORCID 0000-0001-6295-7455
Yunfeng WangENT Institute, Department of Otorhinolaryngology, EYE & ENT Hospital, Fudan University, Shanghai 200031, China.ORCID 0000-0002-3477-1562

Funding

Leadership Project of Chunshen Pyramid Talents Program 202305National Natural Science Foundation of China 82271167Top-notch Project of Shanghai Oriental Talents Program none
6 · The paper itself

Abstract

Hereditary sensorineural hearing loss (SNHL) represents a significant global public health burden. DFNX2, an X-linked form of non-syndromic SNHL, is caused by pathogenic variants in the

Indexed as

Frameshift mutationgenetics of hearing lossPOU3F4 geneX-linked deafness 2

Identifiers

PMID42355396
PMCPMC13302508

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.