Evidence map›Paper›PMID 42356550›Full record

ArticlePharmaceuticals (Basel, Switzerland)2026

Modulation of Mu-Opioid Receptor Expression and Functional Impairment of Natural Killer Cells in Neuropathic Pain: Implications for Biomarker Discovery and Personalized Therapies.

Lucia Carmela Passacatini, Saverio Nucera, Rosamaria Caminiti, Valentina Malafoglia, Valeria Mazza, Leonardo Lupacchini, Stefania Proietti, Laura Vitiello, Roberta Macrì, Maria Serra and 8 more

Abstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Lucia Carmela PassacatiniPain Physiology and Pharmacology, IRCCS San Raffaele Roma, 00166 Rome, Italy.
Saverio NuceraDepartment of Health Sciences, Institute of Research for Food Safety and Health (IRC-FSH), University "Magna Græcia" of Catanzaro, 88100 Catanzaro, Italy.ORCID 0000-0002-0000-4015
Rosamaria CaminitiDepartment of Health Sciences, Institute of Research for Food Safety and Health (IRC-FSH), University "Magna Græcia" of Catanzaro, 88100 Catanzaro, Italy.
Valentina MalafogliaPain Physiology and Pharmacology, IRCCS San Raffaele Roma, 00166 Rome, Italy.ORCID 0000-0002-1533-704X
Valeria MazzaDepartment of Medical and Clinical Surgery, University "Magna Græcia" of Catanzaro, 88100 Catanzaro, Italy.
Leonardo LupacchiniLaboratory of Molecular and Cellular Neurobiology, IRCCS San Raffaele Roma, 00166 Rome, Italy.ORCID 0000-0002-9172-7461
Stefania ProiettiAgea, Coordinating Body, 00185 Rome, Italy.
Laura VitielloDepartment of Human Sciences and Quality of Life Promotion, San Raffaele University, 00166 Rome, Italy.ORCID 0000-0003-0776-3601
Roberta MacrìDepartment of Health Sciences, Institute of Research for Food Safety and Health (IRC-FSH), University "Magna Græcia" of Catanzaro, 88100 Catanzaro, Italy.ORCID 0000-0002-2345-6751
Maria SerraDepartment of Health Sciences, Institute of Research for Food Safety and Health (IRC-FSH), University "Magna Græcia" of Catanzaro, 88100 Catanzaro, Italy.ORCID 0009-0005-7736-2207
Francesca OppedisanoDepartment of Health Sciences, Institute of Research for Food Safety and Health (IRC-FSH), University "Magna Græcia" of Catanzaro, 88100 Catanzaro, Italy.ORCID 0000-0003-0930-8987
Jessica MaiuoloDepartment of Health Sciences, Institute of Research for Food Safety and Health (IRC-FSH), University "Magna Græcia" of Catanzaro, 88100 Catanzaro, Italy.
Cinzia GarofaloDepartment of Experimental and Clinical Medicine, University "Magna Græcia" of Catanzaro, 88100 Catanzaro, Italy.
Carlo TominoIRCCS San Raffaele Roma, 00166 Rome, Italy.ORCID 0000-0003-1823-2195
Vincenzo MollaceDepartment of Health Sciences, Institute of Research for Food Safety and Health (IRC-FSH), University "Magna Græcia" of Catanzaro, 88100 Catanzaro, Italy.
Sara IlariPain Physiology and Pharmacology, IRCCS San Raffaele Roma, 00166 Rome, Italy.ORCID 0000-0002-6756-6530
William RaffaeliISAL Foundation, Institute for Research on Pain, 47921 Rimini, Italy.
Carolina MuscoliDepartment of Health Sciences, Institute of Research for Food Safety and Health (IRC-FSH), University "Magna Græcia" of Catanzaro, 88100 Catanzaro, Italy.ORCID 0000-0002-1047-4467

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

chronic constriction injurychronic neuropathic painchronic pain biomarkersdegranulationnatural killer cellspain biomarkersμ-opioid receptor

Identifiers

PMID42356550
PMCPMC13306064

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.