Evidence mapPaperPMID 42357299Full record

ArticlePharmaceutics2026

Synergistic Inhibition of Colorectal Cancer Growth by Combined PI3K and COX-2 Blockade in Cell Lines and Patient-Derived Organoids.

Emily Nghiem, Ariel Tzamarot, Terence Li, Zimo Huang, Mahshid Mohammadi, Dior Dedushi, Yvonne Saenger, Fernand Bteich, Chaoyuan Kuang

Abstract read
In one paragraph

Article in Pharmaceutics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Emily NghiemDepartment of Surgery, Albert Einstein College of Medicine, and Montefiore Medical Center, Bronx, NY 10467, USA.ORCID 0009-0001-5157-7198
Ariel TzamarotMontefiore Einstein Comprehensive Cancer Center, Albert Einstein College of Medicine, Bronx, NY 10461, USA.ORCID 0009-0001-3339-9236
Terence LiMontefiore Einstein Comprehensive Cancer Center, Albert Einstein College of Medicine, Bronx, NY 10461, USA.ORCID 0009-0007-7599-0001
Zimo HuangMontefiore Einstein Comprehensive Cancer Center, Albert Einstein College of Medicine, Bronx, NY 10461, USA.ORCID 0009-0009-5811-8400
Mahshid MohammadiMontefiore Einstein Comprehensive Cancer Center, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Dior DedushiMontefiore Einstein Comprehensive Cancer Center, Albert Einstein College of Medicine, Bronx, NY 10461, USA.ORCID 0009-0002-7994-6319
Yvonne SaengerMontefiore Einstein Comprehensive Cancer Center, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Fernand BteichMontefiore Einstein Comprehensive Cancer Center, Albert Einstein College of Medicine, Bronx, NY 10461, USA.ORCID 0009-0002-3065-5924
Chaoyuan KuangMontefiore Einstein Comprehensive Cancer Center, Albert Einstein College of Medicine, Bronx, NY 10461, USA.ORCID 0000-0002-8984-3906

Funding

WORD PROCESSORP30CA013330 · YESHIVA UNIVERSITY · 1985 to 2025
$27.5M
Applying pathomics to establish a biosignature for aggressive skin melanomaR01CA260375 · NCI · ALBERT EINSTEIN COLLEGE OF MEDICINE · 2023 to 2025
$1.2M
NIH HHS P30CA013330NIH HHS R01CA260375NIH HHS R42CA287679NIH HHS S10OD026852NIH HHS T32CA200561
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

celecoxibcolorectal cancerCOX-2inavolisiborganoidsPI3KαPIK3CApreclinical study

Identifiers

PMID42357299
PMCPMC13305696

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.