Evidence map›Paper›PMID 42357348›Full record

ReviewPharmaceutics2026

Stimuli-Responsive Peptides for Targeted Anticancer Drug Delivery: Current Advances and Future Outlook.

Oindrila Palit, Ankita Das, Supriya Bharti, Eirinaios I Vrettos, Sankarprasad Bhuniya

Abstract readReview
In one paragraph

Review in Pharmaceutics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Oindrila PalitCentre for Interdisciplinary Sciences, JIS Institute of Advanced Studies and Research, JIS University, 51, South Nayabaz, GIP Colony, Santragachi, Nibra, Howrah 711302, West Bengal, India.ORCID 0009-0008-2163-6119
Ankita DasCentre for Interdisciplinary Sciences, JIS Institute of Advanced Studies and Research, JIS University, 51, South Nayabaz, GIP Colony, Santragachi, Nibra, Howrah 711302, West Bengal, India.ORCID 0009-0001-2081-9131
Supriya BhartiCentre for Interdisciplinary Sciences, JIS Institute of Advanced Studies and Research, JIS University, 51, South Nayabaz, GIP Colony, Santragachi, Nibra, Howrah 711302, West Bengal, India.ORCID 0009-0009-2774-5145
Eirinaios I VrettosDepartment of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.ORCID 0000-0002-4801-1900
Sankarprasad BhuniyaCentre for Interdisciplinary Sciences, JIS Institute of Advanced Studies and Research, JIS University, 51, South Nayabaz, GIP Colony, Santragachi, Nibra, Howrah 711302, West Bengal, India.ORCID 0000-0001-5080-0936

Funding

Science and Engineering Research Board CRG/2023/005905
6 · The paper itself

Abstract

Efficient delivery systems are essential for transporting chemotherapeutic agents to target sites, enhancing cellular uptake and reducing off-target side effects. Peptides, owing to their intrinsic biocompatibility and structural tunability, have emerged as promising carriers for delivering labile chemotherapeutics and improving pharmacokinetics and therapeutic outcomes. Along these lines, a wide variety of peptide-based delivery strategies have been developed to achieve desirable pharmaceutical properties for anticancer agents. Particularly, stimuli-responsive peptide-based nanocarriers have attracted high levels of attention due to their ability to exploit overexpressed or tumor-specific stimuli, enabling selective disassembly and controlled drug release within cancer cells. In this review, we highlight recent advances in the development of stimuli-responsive peptide nanocarriers and their applications in anticancer therapy, and discuss key challenges and future directions toward their clinical translation.

Indexed as

apoptosisenzymeshypoxiain vivopeptideROSstimuli-responsivetumor

Identifiers

PMID42357348
PMCPMC13305868

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.