ReviewPharmaceutics2026
Mechanisms and Therapeutic Targets of Botanicals Derived from Asteraceae Plant Species.
Review in Pharmaceutics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
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Authors and funding
4 authors.
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Abstract
The Asteraceae family represents one of the largest groups of medicinal plants, widely used in traditional medicine and increasingly investigated for its pharmacological potential. This review summarizes current evidence on the botanicals derived from Asteraceae plant species and their molecular mechanisms of action against inflammation and cancer. Major classes of bioactive compounds in extracts are discussed in relation to their modulation of key signaling pathways and therapeutic targets such as NF-κB, MAPK, PI3K/Akt, COX-2, iNOS, and apoptotic regulators (Bax/Bcl-2, caspases). A literature search covering studies published between 2022 and 2026 was conducted. Evidence from in vitro, in vivo, and in silico studies demonstrates that Asteraceae-derived botanicals exert therapeutic effects through antioxidant activity, cytokine suppression, enzyme inhibition, and regulation of gene expression. Overall, the mechanistic insights presented herein support the rational use of Asteraceae medicinal plants and identify promising lead compounds for drug discovery and development.
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Registered trials
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