ReviewVeterinary sciences2026
Quorum Sensing Modulators as Antibiotic Alternatives in Animal Production: From Bacterial Signaling to Gut Health and Performance.
Review in Veterinary sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Plant-Derived Compounds as Antibiotic Adjuvants Against Drug-Resistant ESKAPE Pathogens: Mechanisms of Action, Synergistic Strategies, and Translational Challenges.Antibiotics (Basel, Switzerland) · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
In intensive animal production, the overuse of antibiotics has exacerbated bacterial antimicrobial resistance and environmental pollution. Together with gut microbiota dysbiosis and recurrent disease outbreaks, these challenges severely constrain the sector's high-quality development. Quorum sensing (QS), a cell-density-dependent bacterial communication mechanism, can be modulated through agents that specifically inhibit or activate QS circuitry to regulate microbial community functions. Such QS modulators possess notable advantages, such as environmental benignity and high target specificity, and thus offer innovative strategies to decrease antibiotic reliance, enhance production efficiency, and reduce environmental emissions. This review examines QS modulators sourced from plants, microorganisms, animals, and synthetic processes, while highlighting key challenges such as environmental interference, resistance development, high costs, and the lack of standardized biosafety evaluations. Future research should focus on enhancing specificity, stability, affordability, and safety, with an emphasis on rational design, synergistic systems, improved manufacturing processes, and multi-target modulators. This review may provide a theoretical basis for translating QS-regulation technologies into farm-level applications, thereby advancing sustainable animal production and antibiotic-free husbandry.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.