Clinical utility of the gastrointestinal dysfunction score versus acute gastrointestinal injury grade for short-term risk stratification in critically ill patients: evidence from two prospective cohorts.

Yanhua Li, Youquan Wang, Yuhan Zhang, Feng Zhang, Lu Ke, Dong Zhang

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Article in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed

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1 · What the graph read from it

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2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Yanhua LiDepartment of Critical Care Medicine, The First Hospital of Jilin University, Changchun, China.

Youquan WangDepartment of Critical Care Medicine, The First Hospital of Jilin University, Changchun, China.

Yuhan ZhangDepartment of Critical Care Medicine, The First Hospital of Jilin University, Changchun, China.

Feng ZhangDepartment of Critical Care Medicine, The First Hospital of Jilin University, Changchun, China.

Lu KeDepartment of Critical Care Medicine, Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu, China.

Dong ZhangDepartment of Critical Care Medicine, The First Hospital of Jilin University, Changchun, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: To compare whether GIDS or AGI grade is more strongly associated with short-term outcomes in critically ill patients. Methods: We conducted a secondary analysis of two prospectively collected cohorts. The primary analyses was conducted using the single-center FJLU cohort of critically ill adults with organ failure (SOFA ≥2 within 24 h of ICU admission), and externally validated using the multicentre NEED trial cohort. The primary outcomes were 28-day mortality and ICU-free days to day 28. Associations with mortality were assessed using Cox models, discrimination by ROC curves with the DeLong test, and trends in ICU-free days using the Jonckheere-Terpstra test. Results: A total of 1,995 patients were included (FJLU Conclusion: Both GIDS and AGI were associated with short-term outcomes in critically ill patients, with comparable overall prognostic performance. GIDS may provide additional value in patients with greater illness severity. Clinical trial registration: Identifier ChiCTR2300071370; ISRCTN12233792.

Indexed as

acute gastrointestinal injuryclinical outcomescritically ill patientsgastrointestinalgastrointestinal dysfunction score

Identifiers

PMID42358303

DOI10.3389/fnut.2026.1870956

PMCPMC13292638

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.