ArticleGeneral psychiatry2026
Associations between wearable-device-measured daytime and nighttime light exposures and dementia risk: A prospective cohort study.
Article in General psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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14 authors.
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Abstract
Background: Identifying reliable predictors for dementia remains a critical unmet need. Light exposure plays a crucial role in regulating circadian rhythms, which influence cognitive function. However, the association between light exposure and dementia risk remains unclear. Aims: This study examined the associations of daytime and nighttime light exposure with dementia risk. Methods: A total of 87 577 dementia-free participants (mean age: 62.36 years; 56.98% female) were included. Daytime and nighttime light exposures were measured using 7-day free-living wrist-worn accelerometry. Incident dementia was identified from primary care, hospital inpatient admissions and death registry data. Cox proportional hazards models assessed associations, and mediation analyses evaluated circadian rest-activity rhythms (CRARs), brain structures and vitamin D as potential mediators. Results: Over a median follow-up of 8.1 years, 741 participants developed dementia. Daytime light exposure above 1000 lux was associated with reduced dementia risk (hazard ratio [HR] 0.84, 95% confidence interval [CI] 0.71-0.99, Conclusions: High levels of daytime light exposure were significantly associated with lower dementia risk. Further research should explore its role in dementia screening and inform the development of light-based interventions.
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