ArticleFrontiers in nephrology2026
Exploring the relationship between serum vitamin D and atherosclerosis in hemodialysis patients: a cross-sectional study.
Article in Frontiers in nephrology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07200804 (Exploring the Relationship Between Serum Vitamin D and Atherosclerosis in Hemodialysis Patients), which is not on this map. Not yet cited in PubMed.
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Exploring the Relationship Between Serum Vitamin D and Atherosclerosis in Hemodialysis Patients: A Cross-sectional Study
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5 authors.
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Abstract
Objective: To check if there is a link between good vitamin D levels in the blood and subclinical atherosclerosis in people on hemodialysis. Methods: Ninety end-stage renal disease patients undergoing regular hemodialysis were included in a cross-sectional study. Based on carotid intima-media thickness (CIMT), patients were grouped into Group A (n = 44) with normal CIMT and Group B (n = 46) with increased CIMT. Clinical assessments, laboratory parameters (serum vitamin D, lipid profiles, and inflammatory markers), and CIMT were measured using carotid ultrasound. The researcher compared students' t-tests with quantitative variables, while employing the Chi-square or Fisher's exact test with qualitative variables. Results: A positive correlation was observed between serum vitamin D and calcium (p = 0.010) and triglycerides (p = 0.025). Serum vitamin D showed a negative correlation with weight, serum alkaline phosphatase, and urea. No significant differences were found between the two groups in terms of demographic factors, BMI, hemodialysis duration, diabetes prevalence, or vitamin D supplementation. Group B exhibited elevated serum calcium levels (p = 0.008). Multivariate analysis found weight as an independent predictor of low vitamin D levels (p = 0.016). Conclusion: Serum calcium levels were significantly associated with CIMT; however, no correlation was seen between vitamin D levels and CIMT. Trial registration: registered at clinicaltrials.gov (ID: NCT07200804).
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