ArticleFrontiers in reproductive health2026
Identification of genes differentially expressed in granulosa cells from women with high vs. low ovarian responsiveness.
Article in Frontiers in reproductive health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: A better understanding of the response of granulosa cells to exogenous hormone stimulation and how this impacts the complex interplay between the granulosa cells and the oocyte is crucial for the optimal management of infertile couples seeking IVF treatment. Methods: Granulosa and cumulus cells (G + CCs) from women with different degrees of ovarian responsiveness to controlled ovarian hyperstimulation (COH) were purified and used for RNA sequencing (RNA-seq) analysis and downstream bioinformatic analyses. Results: RNA-seq analysis on G + CCs purified from 16 patients undergoing hormone treatment for Conclusions: Our study (i) offers potential insight into the underlying pathophysiologic processes underlying weak ovarian responses, (ii) identifies genes that are candidates to define weak ovarian responders, and (iii) identifies signaling pathways that when modulated, could potentially be used to improve IVF outcomes.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.