ArticleInternational journal of general medicine2026
Albumin-to-Globulin Ratio as a Predictor of Disease Severity in Emergency Department Patients Presenting with Flank Pain.
Article in International journal of general medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Flank pain is a common emergency department (ED) presentation with a wide differential diagnosis. The albumin-to-globulin ratio (AGR) reflects both nutritional status and systemic inflammation, but its utility in pre-intervention ED patients with flank pain has not been systematically evaluated. Methods: In this retrospective cross-sectional study, we included 291 consecutive adults who presented to the ED with flank pain and underwent urinary ultrasonography between August 2022 and May 2023. Severe presentation was defined as ≥2 of the following: hydronephrosis, acute kidney injury (creatinine >1.2 mg/dL), elevated CRP (>50 mg/L), or leukocytosis (WBC >12×10 Results: Among 291 patients (mean age 47.5 ± 23.5 years, 46% male), 59 (20.3%) had severe presentations. AGR was significantly lower in the severe group (1.26 ± 0.35 vs 1.55 ± 0.31, Conclusion: AGR is an independent predictor of severe presentation in ED patients with flank pain, but its moderate sensitivity and absence of incremental value beyond CRP and creatinine suggest it should be used as an adjunctive marker rather than a stand-alone screening tool. Prospective validation is needed before integration into ED triage algorithms.
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