Evidence map›Paper›PMID 42358898›Full record

ReviewPediatric investigation2026

Kaposiform hemangioendothelioma: Diagnosis and treatment.

Yi Tian, Yuanyuan Tian, Li Wei, Zigang Xu, Li Li, Lin Ma

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Pediatric investigation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yi TianDepartment of Dermatology Beijing Children's Hospital, Capital Medical University, National Center for Children's Health Beijing China.
Yuanyuan TianDepartment of Dermatology Beijing Children's Hospital, Capital Medical University, National Center for Children's Health Beijing China.ORCID https://orcid.org/0000-0003-2918-7270
Li WeiDepartment of Dermatology Beijing Children's Hospital, Capital Medical University, National Center for Children's Health Beijing China.
Zigang XuDepartment of Dermatology Beijing Children's Hospital, Capital Medical University, National Center for Children's Health Beijing China.
Li LiDepartment of Dermatology Beijing Children's Hospital, Capital Medical University, National Center for Children's Health Beijing China.
Lin MaDepartment of Dermatology Beijing Children's Hospital, Capital Medical University, National Center for Children's Health Beijing China.ORCID https://orcid.org/0000-0001-7625-9842

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Kaposiform hemangioendothelioma (KHE) is a rare borderline vascular tumor that occurs primarily during infancy and childhood. The tumor typically originates in the skin and exhibits invasive growth into deeper tissues, often manifesting as a firm, poorly defined purplish-red mass. Cases of KHE involving visceral organs, including the bone, retroperitoneum, or mediastinum, have also been reported; however, their clinical features are often nonspecific, which may lead to delayed diagnosis. Importantly, these tumors are frequently associated with Kasabach-Merritt phenomenon, a consumptive coagulopathy that represents a major cause of mortality in KHE. Furthermore, tumor location, size, and clinical response to pharmacotherapy are closely associated with patient prognosis. Therefore, early recognition and timely treatment of KHE are essential. This article aims to review the epidemiology, etiology, clinical manifestations, diagnosis, and management of KHE.

Indexed as

Diagnosis and treatmentKaposiform hemangioendotheliomaKasabach‐Merritt phenomenonPathogenesis

Identifiers

PMID42358898
PMCPMC13291430

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.