ArticleMethodsX2026
Simplified method for EEG recordings in mice.
Article in MethodsX, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
3 authors.
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Abstract
Currently, implantation of electroencephalogram (EEG) electrodes in laboratory animals is time-consuming and requires specialized equipment. We present a novel method for EEG recordings in mice that utilizes thin needle electrodes. These electrodes are inserted into the skull at predetermined locations by gently pressing them against the bone surface. To ensure stable fixation of the implant, hook-shaped needles are positioned along the lateral aspects of the skull. The electrodes are connected to a multipin connector and secured to the skull using dental composite, after which the animal is allowed to recover from anesthesia. Importantly, procedures such as skull drilling and screw placement are not required, allowing the entire surgery to be completed in <15 min. Consequently, this EEG implantation approach is rapid and minimally invasive. Results of our studies indicate that EEG recordings obtained with needle electrodes are not inferior to those obtained with screw electrodes. Overall, the method is designed to enhance the accuracy and efficiency of EEG recording studies while improving animal welfare. • Simplifies the placement of EEG electrodes. • Reduces the time required for electrode implantation.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.