Evidence map›Paper›PMID 42363809›Full record

ArticleAdvanced healthcare materials2026

Tailoring Drug Release Profiles From Electrospun Alginate Fibers Through Integration of Mesoporous Silica Nanoparticles.

Carolina Gutierrez Cisneros, Mrinal Gaurav Srivastava, Naiera Zayed, Mara Deknudt, Wim Teughels, Annabel Braem, Arn Mignon

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced healthcare materials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Carolina Gutierrez CisnerosKU Leuven, Department of Materials Engineering (MTM), Leuven, Belgium.
Mrinal Gaurav SrivastavaKU Leuven, Department of Materials Engineering (MTM), Leuven, Belgium.
Naiera ZayedDepartment of Oral Health Sciences, KU Leuven, Leuven, Belgium.ORCID https://orcid.org/0000-0002-7773-8199
Mara DeknudtKU Leuven, Department of Materials Engineering (MTM), Leuven, Belgium.
Wim TeughelsDepartment of Oral Health Sciences, KU Leuven, Leuven, Belgium.ORCID https://orcid.org/0000-0001-7675-5643
Annabel BraemKU Leuven, Department of Materials Engineering (MTM), Leuven, Belgium.
Arn MignonKU Leuven, Department of Materials Engineering (MTM), Leuven, Belgium.ORCID https://orcid.org/0000-0002-4339-8827

Funding

Research Foundation - Flanders (FWO-Vlaanderen) 1S33424NResearch Foundation - Flanders (FWO-Vlaanderen) 1SHFK24NResearch Foundation - Flanders (FWO-Vlaanderen) G095920NResearch Foundation-Flanders (FWO-Vlaanderen)
6 · The paper itself

Abstract

Electrospun hydrogels often lack sufficient mechanical integrity for biomedical applications, while nanoparticle-reinforced systems are commonly associated with synthetic matrices or complex fabrication methods. Here, electrospun methacrylated alginate (AM) fibrous hydrogels reinforced with mesoporous silica nanoparticles (MSNs) are introduced as a simple, biocompatible platform for localized drug delivery. The mats are UV-cross-linked in ethanol to maintain fibrous morphology and allow chlorhexidine (CHX) loading from 0.2 to 5 mg ml

Indexed as

AlginatesNanoparticlesSilicon DioxideAnimalsAnti-Bacterial AgentsChlorhexidineDrug LiberationGlucuronic AcidHexuronic AcidsHydrogelsPorositySpectroscopy, Fourier Transform InfraredAlginatesAnti-Bacterial AgentsChlorhexidineGlucuronic AcidHexuronic AcidsHydrogelsSilicon Dioxidebioactive healingelectrospinningfibrous biocompositenano carriers

Identifiers

PMID42363809
PMCPMC13447901

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.