ArticleVeterinary medicine and science2026
Ocular Manifestations of Canine Parvovirus in Juvenile Dogs: Tear Production, Intraocular Pressure, Fundoscopic Findings, and Ultrasonographic Measurements.
Article in Veterinary medicine and science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
backgroundCanine parvovirus (CPV) is a major cause of haemorrhagic enteritis in juvenile dogs, yet its potential ocular effects have not been systematically investigated.
objectivesTo evaluate whether naturally acquired CPV infection in juvenile dogs is associated with alterations in tear production, intraocular pressure, corneal integrity, fundoscopic findings, and ocular ultrasonographic measurements.
methodsSeventy client-owned dogs under 6 months of age were included: 35 with confirmed CPV infection and 35 healthy controls. Before treatment, all animals underwent standardised ophthalmic examination including Schirmer tear test-I (STT-I), intraocular pressure (IOP) measurement, fluorescein staining, fundoscopic examination, and ocular ultrasonography. In CPV-infected dogs, dehydration severity (mild 5%-8%, moderate 8%-10%, severe ≥10%) was graded clinically for exploratory analyses. Continuous variables were compared using Student's t-test or Mann-Whitney U test, and categorical variables using χ
resultsCPV-infected dogs had significantly lower STT-I and IOP values than controls. Fluorescein staining was positive in 27/35 (77.1%) infected dogs and absent in controls. Fundoscopic abnormalities, including retinal vessel beading, chorioretinitis, and optic neuritis, were detected in 28/35 (80%) infected dogs, whereas all controls had normal findings. Ocular ultrasonographic parameters did not differ between groups. Dehydration severity did not significantly affect STT-I, IOP, or fluorescein results.
conclusionsCPV infection in juvenile dogs is associated with reduced tear production, ocular hypotony, frequent corneal epithelial defects, and posterior segment abnormalities, indicating that CPV may involve both the ocular surface and fundus in addition to the gastrointestinal system.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.