Evidence map›Paper›PMID 42366340›Full record

ArticleBMC endocrine disorders2026

Association of metabolic syndrome and its components with systemic lupus erythematosus.

Zahra Bagheri-Hosseinabadi, Sahar Sadat Pourmirafzali, Mehdi Kafi, Mohammad Amin Lotfi, Mitra Abbasifard

Abstract read
In one paragraph

Article in BMC endocrine disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zahra Bagheri-HosseinabadiMolecular Medicine Research Center, Research Institute of Basic Medical Sciences, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
Sahar Sadat PourmirafzaliStudent Research Committee, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
Mehdi KafiStudent Research Committee, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
Mohammad Amin LotfiClinical Research Development Unit, Ali-Ibn Abi-Talib Hospital, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
Mitra AbbasifardImmunology of Infectious Diseases Research Center, Research Institute of Basic Medical Sciences, Rafsanjan University of Medical Sciences, Rafsanjan, Iran. dr.abbasifard.m@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSystemic lupus erythematosus (SLE) patients might manifest an increased prevalence of Metabolic syndrome (MetS) components like insulin resistance, obesity, and dyslipidemia. Here we aimed to assess the interconnection between MetS components and SLE and attempted to divulge the potential contribution of MetS on SLE development.

methodsWe enrolled 200 cases with SLE whose diagnosis was accomplished by American College of Rheumatology (ACR) criteria. MetS diagnosed was accomplished through the International Diabetes Federation (IDF) criteria.

resultsThe frequency of MetS among the SLE population was 28.5%. SLEDAI was not significantly different between SLE cases with and without MetS (P = 0.3519). CRP level was significantly higher in the SLE cases with MetS compared to those without MetS (P = 0.0412). BMI, FBS, WC (both in males and females), total cholesterol, TG, and LDL were significantly higher in SLE subjects with MetS compared to those without MetS. However, in both males and females, HDL level was significantly lower in SLE subjects with MetS compared to those without MetS. Obesity, CVD, T2D, dyslipidemia, and hypertension were more prevalent in MetS cases among the SLE population.

conclusionsAn increased prevalence of MetS in the SLE population was observed, while these patients did not have worsen disease severity. All conventional components of MetS were associated with MetS development in the SLE population. CLINICAL TRIAL NUMBER: Not applicable.

Indexed as

DyslipidemiasLupus Erythematosus, SystemicMetabolic SyndromeObesityAdultFemaleFollow-Up StudiesHumansInsulin ResistanceMaleMiddle AgedPrevalencePrognosisRisk FactorsDiabetesDyslipidemiaInflammationMetabolic syndromeSystemic lupus erythematosus

Identifiers

PMID42366340
PMCPMC13591809

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.