ArticleMolecular therapy. Nucleic acids2026
A novel role of circCPSF6 regulating antiviral innate immunity via miR-665 and PCBP2-IPS-1 axis in IAV infection.
Article in Molecular therapy. Nucleic acids, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Innate immunity plays a vital role in subverting viral infections via dynamic regulatory networks that calibrate antiviral response and prevent excessive inflammation. These networks are coordinately regulated by coding and non-coding elements of the genome. The non-coding elements, particularly circular RNAs (circRNAs), have emerged as a key modulator of various biological processes, yet their precise function in innate immune response during influenza A virus (IAV) infection remains insufficiently defined. Here, we identified circCPSF6, a conserved circRNA that remains suppressed during IAV infection,
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