ArticleCarbohydrate polymer technologies and applications2023
DMTMM-mediated synthesis of norbornene-modified hyaluronic acid polymers to probe cell-hydrogel interactions.
Article in Carbohydrate polymer technologies and applications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Nascent Extracellular Matrix Converts Biomaterial Cues into Cell Fate Decisions.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Tuning scaffold degradation with non-natural peptidomimetics to control human umbilical vein endothelial cell morphology and vessel formation.Acta biomaterialia · 2026Article
- A robust and user-agnostic step-emulsion platform for scalable microgel fabrication.bioRxiv : the preprint server for biology · 2026Article
- Reprogramming Dedifferentiation Regulatory Networks Preserves Human Chondrocyte Phenotypes.bioRxiv : the preprint server for biology · 2026Article
- Norbornene Homopolymerization Limits Cell Spreading in Thiol-Ene Photoclick Hydrogels.Advanced healthcare materials · 2025Article
- Effects of Stiffness and Degradability on Cardiac Fibroblast Contractility and Extracellular Matrix Secretion in Three-Dimensional Hydrogel Scaffolds.ACS biomaterials science & engineering · 2025Article
- Hydrogel Viscoelasticity Modulates Cell Nascent Extracellular Matrix Deposition.Macromolecular rapid communications · 2025Article
- Tuning Scaffold Degradation with Non-Natural Peptidomimetics to Control Human Umbilical Vein Endothelial Cell Morphology and Vessel Formation.bioRxiv : the preprint server for biology · 2025Article
- Mechanical Cues Regulate Estrogen and Progesterone-Induced Nascent ECM Deposition by Human Endometrial Stromal Cells.bioRxiv : the preprint server for biology · 2025Article
- Lung tissue viscoelasticity is preserved with bleomycin-induced fibrosis in mice.bioRxiv : the preprint server for biology · 2025Article
- Biodegradable Polymers for Plant Nutrient Delivery and Recovery.Macromolecular bioscience · 2025Review
- Hyaluronic acid as a versatile building block for the development of biofunctional hydrogels: In vitro models and preclinical innovations.Materials today. Bio · 2025Article
- Measurement and Comparison of Hyaluronic Acid Hydrogel Mechanics Across Length Scales.Journal of biomedical materials research. Part A · 2025Article
- A Comparative Study between Thiol-Ene and Acrylate Photocrosslinkable Hyaluronic Acid Hydrogel Inks for Digital Light Processing.Macromolecular bioscience · 2025Article
- Nascent matrix deposition supports alveolar organoid formation from aggregates in synthetic hydrogels.Stem cell reports · 2025Article
- Nascent matrix deposition supports alveolar organoid formation from aggregates in synthetic hydrogels.bioRxiv : the preprint server for biology · 2024Article
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3 authors.
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Abstract
Synthesis of chemically modified hyaluronic acid (HA) polymers has enabled the fabrication of hydrogels, such as norbornene-modified HA (NorHA) hydrogels that can provide tunable mechanical properties. However, current protocols for the synthesis of NorHA polymers rely on the use of dimethyl sulfoxide (DMSO), a solvent that is cost-intensive and requires extensive dialysis to be removed. To address this limitation, we developed an organic solvent-free NorHA synthesis protocol based on the triazine derivative 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride (DMTMM) which enables control over the degree of substituted norbornene groups and hydrogel mechanical properties. Our study further demonstrates the incorporation of enzymatically degradable crosslinkers to fabricate NorHA hydrogels as an
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