Evidence map›Paper›PMID 42367758›Full record

SynthesisFrontiers in immunology2026

The role of CD8

ZiChao Chen, Hao Hu, Die Hu, QinChuan Du, HuanZhi Yang, RongHua Xu, Peng Yu, XingBo Hu, Jun Hu

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

ZiChao Chen *Organization Kunming Calmette International Hospital, KunMing, China.
Hao Hu *Organization Xiangnan University, ChenZhou, China.
Die HuOrganization Hunan University of Medicine, HuaiHua, China.
QinChuan DuOrganization Kunming Calmette International Hospital, KunMing, China.
HuanZhi YangOrganization Kunming Calmette International Hospital, KunMing, China.
RongHua XuOrganization Kunming Calmette International Hospital, KunMing, China.
Peng YuOrganization Kunming Calmette International Hospital, KunMing, China.
XingBo HuOrganization Kunming Calmette International Hospital, KunMing, China.
Jun HuOrganization Kunming Calmette International Hospital, KunMing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Osteoporosis weakens the skeleton by lowering bone mass and damaging bone microarchitecture. A growing body of evidence points to disruptions in osteoimmune homeostasis as a key driver of this disease. In particular, apoptosis of bone cells and immune cells appears to be a critical contributing mechanism. Within the bone marrow, CD8 Methods: We performed a narrative review of recent studies on CD8 Results: CD8 Discussion: Our synthesis shows that CD8

Indexed as

CD8-Positive T-LymphocytesOsteoporosisAnimalsHumansCD8+ T cellscellular senescenceimmunotherapyinterferon-γosteoimmunologyosteoporosis

Identifiers

PMID42367758
PMCPMC13303203

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.