ArticlebioRxiv : the preprint server for biology2026
Identification of UCB-9721 as a potent inhibitor of MyoA, the essential class XIV myosin motor of apicomplexan parasites.
Anne K Snyder, Filomena Tedesco, Anne Kelsen, Eddie Wehri, Binod Nepal, Jose Teixeira, Emmett Dews, Sachie Kanatani, Kyle Kasprzak, Jonathan Oliva and 12 more
Abstract readPreprint
In one paragraphArticle in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
22 authors.
Anne K SnyderDepartment of Microbiology and Molecular Genetics, University of Vermont Larner College of Medicine, Burlington, Vermont, USA.ORCID 0000-0003-3022-2213 Filomena TedescoSchool of Chemistry and Biomedical Sciences Research Complex, University of St. Andrews and EaStCHEM, St Andrews, Fife, Scotland, United Kingdom.
Anne KelsenDepartment of Microbiology and Molecular Genetics, University of Vermont Larner College of Medicine, Burlington, Vermont, USA.
Binod NepalDepartment of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, Pennsylvania, USA.ORCID 0009-0000-6193-1210 Jose TeixeiraDepartment of Medicine, University of Vermont Larner College of Medicine, Burlington, Vermont, USA.
Emmett DewsDepartment of Microbiology and Molecular Genetics, University of Vermont Larner College of Medicine, Burlington, Vermont, USA.
Sachie KanataniDepartment of Molecular Microbiology and Immunology, and the Johns Hopkins Malaria Research Institute, Johns Hopkins School of Public Health, Baltimore, Maryland, USA.ORCID 0000-0002-7072-0447 Kyle KasprzakDepartment of Microbiology and Molecular Genetics, University of Vermont Larner College of Medicine, Burlington, Vermont, USA.
Jonathan OlivaDepartment of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St. Louis, Missouri, USA.ORCID 0009-0006-0388-0797 Kaesi MorelliDepartment of Microbiology and Molecular Genetics, University of Vermont Larner College of Medicine, Burlington, Vermont, USA.ORCID 0000-0002-9637-030X Samantha Beck PrevisDepartment of Molecular Physiology and Biophysics, University of Vermont Larner College of Medicine, Burlington, Vermont, USA.ORCID 0000-0002-5516-1579 Bruno Martorelli di GenovaDepartment of Microbiology and Molecular Genetics, University of Vermont Larner College of Medicine, Burlington, Vermont, USA.ORCID 0000-0001-9983-1856 Fran SverdrupDepartment of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St. Louis, Missouri, USA.ORCID 0000-0001-5843-5734 Martin J BoulangerDepartment of Biochemistry and Microbiology, University of Victoria, Victoria, British Columbia, Canada.ORCID 0000-0001-6835-9309 Photini SinnisDepartment of Molecular Microbiology and Immunology, and the Johns Hopkins Malaria Research Institute, Johns Hopkins School of Public Health, Baltimore, Maryland, USA.ORCID 0000-0003-2954-7547 Christopher D HustonDepartment of Medicine, University of Vermont Larner College of Medicine, Burlington, Vermont, USA.
Sandhya KortagereDepartment of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, Pennsylvania, USA.ORCID 0000-0002-3532-8669 David M WarshawDepartment of Molecular Physiology and Biophysics, University of Vermont Larner College of Medicine, Burlington, Vermont, USA.ORCID 0000-0002-0071-8798 Julia SchaletzkyMolecular Therapeutics Initiative, University of California Berkeley, California, USA.ORCID 0000-0002-7437-4684 Nicholas J WestwoodSchool of Chemistry and Biomedical Sciences Research Complex, University of St. Andrews and EaStCHEM, St Andrews, Fife, Scotland, United Kingdom.ORCID 0000-0003-0630-0138 Gary E WardDepartment of Microbiology and Molecular Genetics, University of Vermont Larner College of Medicine, Burlington, Vermont, USA.ORCID 0000-0003-4138-3055 Funding
The Biochemical Basis for the Mechanics of CytokinesisR01GM066817 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI ROBINSON, DOUGLAS N · 2003 to 2025
$7.3MMultiscale analysis of MyosinA-based motility in Toxoplasma gondiiR01AI139201 · NIAID · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI WARD, GARY E · 2019 to 2023
$2.8MVermont Immunology/Infectious Diseases Training GrantT32AI055402 · NIAID · UNIVERSITY OF VERMONT &ST AGRIC COLLEGE · PI GARY E WARD · 2005 to 2026
$2.7MSIGNAL TRANSDUCTION AND DICTYOSTELIUM DEVELOPMENTR01GM028007 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI DEVREOTES, PETER N · 1985 to 2004
$2.4MEquipment supplement - Refeyn TwoMP iSCAT microscopeR35GM141743 · NIGMS · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI WARSHAW, DAVID M · 2021 to 2025
$2.3MInvestigating the Mechanisms Underlying Mosquito Infectiousness in MalariaR21AI178535 · NIAID · JOHNS HOPKINS UNIVERSITY · PI SINNIS, PHOTINI · 2024 to 2025
$473kLiquid chromatography and mass spectrometry instrument systemS10OD032206 · OD · SAINT LOUIS UNIVERSITY · PI SVERDRUP, FRANCIS MICHAEL · 2022 to 2022
$250kImage-based quantification of Plasmodium sporozoites in a single oocyst using deep learning-based segmentation and 3D reconstructionR03AI180804 · NIAID · JOHNS HOPKINS UNIVERSITY · PI KANATANI, SACHIE, SINNIS, PHOTINI · 2024 to 2025
$161kNIAID NIH HHS R01 AI139201NIAID NIH HHS R03 AI180804NIAID NIH HHS R21 AI178535NIAID NIH HHS T32 AI055402NIGMS NIH HHS R01 GM028007NIGMS NIH HHS R01 GM066817NIGMS NIH HHS R35 GM141743NIH HHS S10 OD032206
6 · The paper itselfAbstract
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PMID42367977
PMCPMC13308002
What Socratic holds
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