Evidence map›Paper›PMID 42368012›Full record

ArticlebioRxiv : the preprint server for biology2026

Neuraminidase1 Activity Contributes to Vasopressin Receptor-mediated Augmentation of Water and Electrolyte Retention by the Kidney in

Gagandeep Kaur, Akua Serwaa-Bonsu, Kisho Miyasako, James A McCormick, Patrick Osei-Owusu

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gagandeep KaurDepartment of Physiology & Biophysics, Case Western Reserve University School of Medicine, Cleveland, Ohio, United States.ORCID 0009-0000-1856-8233
Akua Serwaa-BonsuDepartment of Physiology & Biophysics, Case Western Reserve University School of Medicine, Cleveland, Ohio, United States.
Kisho MiyasakoDepartment of Medicine, Oregon Health & Science University, Portland, Oregon, United States.
James A McCormickDepartment of Medicine, Oregon Health & Science University, Portland, Oregon, United States.ORCID 0000-0003-4000-6653
Patrick Osei-OwusuDepartment of Physiology & Biophysics, Case Western Reserve University School of Medicine, Cleveland, Ohio, United States.ORCID 0000-0002-4581-7044

Funding

Regulation of sodium transport and blood pressure by SPAK/OSR1 kinasesR01DK098141 · NIDDK · OREGON HEALTH & SCIENCE UNIVERSITY · PI JAMES A MCCORMICK, Ujwal Shinde · 2014 to 2026
$4.2M
Vascular Pyruvate Kinase M2 in HypertensionR01HL174004 · NHLBI · UNIVERSITY OF SOUTH FLORIDA · PI SATORU EGUCHI, Patrick Osei-Owusu · 2025 to 2026
$1.4M
Posttranslational regulation of Regulator of G protein Signaling 2 (RGS2)R01GM143493 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI SJOGREN, BENITA JENNY · 2022 to 2025
$1.4M
Magnesium handling by the distal nephronR01DK132066 · NIDDK · OREGON HEALTH & SCIENCE UNIVERSITY · PI JAMES A MCCORMICK · 2023 to 2026
$1.3M
NHLBI NIH HHS R01 HL174004NIDDK NIH HHS R01 DK098141NIDDK NIH HHS R01 DK132066NIGMS NIH HHS R01 GM143493
6 · The paper itself

Abstract

Elastin haploinsufficiency is a primary determinant of arteriopathy and hypertension that hallmark Williams syndrome (WS), a rare genetic disorder resulting from microdeletion of genes on human chromosome 7, including the elastin gene (

Indexed as

elastin haploinsufficiencyextracellular fluid volume regulationneuraminidase-1renal functionvasopressin receptors

Identifiers

PMID42368012
PMCPMC13308021

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.