Evidence map›Paper›PMID 42368274›Full record

ReviewFrontiers in pediatrics2026

Association between breastfeeding and lower risk of behavioral problems in children: a systematic review and meta-analysis.

Xue Liu, Miao Liu, Hongli Chen, Yinan Zheng, Qian Zhao, Zhongli Li, Yuling Zhou, Lilian Chen

Abstract readReview
In one paragraph

Review in Frontiers in pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xue LiuCollege of Nursing, Shanxi University of Chinese Medicine, Jinzhong, Shanxi, China.
Miao LiuCollege of Nursing, Shanxi University of Chinese Medicine, Jinzhong, Shanxi, China.
Hongli ChenCollege of Nursing, Shanxi University of Chinese Medicine, Jinzhong, Shanxi, China.
Yinan ZhengCollege of Nursing, Shanxi University of Chinese Medicine, Jinzhong, Shanxi, China.
Qian ZhaoDepartment of Child Health Care, Shenzhen Guangming Maternity & Child Healthcare Hospital, Shenzhen, Guangdong, China.
Zhongli LiDepartment of Child Health Care, Shenzhen Guangming Maternity & Child Healthcare Hospital, Shenzhen, Guangdong, China.
Yuling ZhouDepartment of Child Health Care, Shenzhen Guangming Maternity & Child Healthcare Hospital, Shenzhen, Guangdong, China.
Lilian ChenCollege of Nursing, Shanxi University of Chinese Medicine, Jinzhong, Shanxi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To systematically evaluate the association between breastfeeding and the risk of behavioral problems in children, and to provide evidence-based support for early prevention strategies. Methods: PubMed, the Cochrane Library, Embase, Web of Science, SinoMed, CNKI, WanFang Data, and VIP were systematically searched from database inception to November 2025 for observational studies examining the association between breastfeeding and behavioral problems in children. Two reviewers independently screened the literature, extracted data, and assessed study quality. Meta-analysis was performed using Stata MP 18.0, and pooled odds ratios (ORs) with 95% confidence intervals (CIs) were calculated. Results: Ten studies involving 69,621 children were included, comprising four cohort studies and six cross-sectional studies. Breastfeeding was significantly associated with a lower risk of overall behavioral problems (OR = 0.66, 95% CI: 0.51-0.86, Conclusions: The findings suggest a potential association between breastfeeding and a lower risk of behavioral problems in children. However, the available evidence is limited, and residual confounding and publication bias cannot be excluded. Further high-quality prospective studies are needed to clarify the nature, magnitude, and potential causal mechanisms underlying these associations. Systematic Review Registration: https://www.crd.york.ac.uk/prospero/, identifier CRD420251233415.

Indexed as

behavioral problemsbreastfeedingchildrenexternalizing behavioral problemsinternalizing behavioral problemsmeta-analysissystematic review

Identifiers

PMID42368274
PMCPMC13303373

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.